CHEMBL158740


SMILES CC1CCN(CCc2cc3cc(-c4ccc(C#N)cc4)ccc3o2)CC1
InChIKey HRPKXNNRDDPCBN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 7.82 7.82 7.82 ChEMBL
H3 HRH3 Rat Histamine A pKi 7.79 7.79 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database