CHEMBL1188501


SMILES NC1=Nc2ccc(Cl)cc2CN1
InChIKey XXJMPUMRHCNWPW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 181.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.09 6.24 6.33 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.61 6.61 6.61 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.08 6.09 6.1 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.94 5.94 5.94 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.5 6.53 6.55 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.24 5.27 5.29 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.19 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database