GproteinDb contains reference data, interactive visualization and experiment design tools for G proteins. GproteinDb curates sequence alignments, structures and mutations from literature. Interactive diagrams visualise G protein residues (e.g. snakeplot) and interactions with receptors.

GproteinDb is developed by the David Gloriam group, integrates data from the research community and maintains an active collaboration with the Guide To Pharmacology (IUPHAR), GPCRmd, ERNEST and DrGPCR. If you use the GproteinDb, please remember to cite us.

GproteinDb statistics

  • 16 Human G proteins
  • 317 Species orthologs
  • Experimental structures
  • 306 G proteins
  • 160 GPCR-G protein complexes
  • Structure models
  • 3,067 GPCR-G protein complexes
  • 132 Refined complex structures
  • Structure interactions
  • 4,753 GPCR-G protein interface
  • Couplings
  • 4,027 GPCR-G protein coupling
  • Mutations
  • 54 Interface mutations
GPCRdb, GproteinDb, and ArrestinDb had 50,781 different users since this date last year and 5,532 users in the last 30 days (Google Analytics).

Latest release

Dec. 23, 2021
  • Updated GPCR and G protein structures.
  • Minor bug and performance fixes.