Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 32 | 85 | 12 | 6 | - | 135 |
Receptor - G protein complexes | 382 | 462 | 133 | 15 | 1 | 993 |
Total structures | 414 | 547 | 145 | 21 | 1 | 1128 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 238 (51) | 420 (131) | 121 (52) | 7 (5) | - | 786 (239) |
Class B1 | 118 (15) | 2 (2) | 3 (2) | - | - | 123 (19) |
Class B2 | 14 (7) | 6 (3) | 4 (3) | 8 (7) | - | 32 (20) |
Class C | 1 (1) | 13 (7) | 4 (1) | - | - | 18 (9) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 5 (3) | 5 (1) | 1 (1) | - | - | 11 (5) |
Class T2 | - | 16 (3) | - | - | - | 16 (3) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2025-01-01.
Structural coverage of GPCR-G protein complexes.
Receptor names:
Class A
(Rhodopsin)
G Protein complexes
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1