Number of G protein structures

Structures Gs Gi/o Gq/11 G12/13 GPa1 Total
Non complexed G protein 32 85 12 6 - 135
Receptor - G protein complexes 382 462 133 15 1 993
Total structures 414 547 145 21 1 1128


Number of GPCR-G protein structures (distinct complexes)

Receptor Class Gs Gi/o Gq/11 G12/13 GPa1 Total
Class A 238 (51) 420 (131) 121 (52) 7 (5) - 786 (239)
Class B1 118 (15) 2 (2) 3 (2) - - 123 (19)
Class B2 14 (7) 6 (3) 4 (3) 8 (7) - 32 (20)
Class C 1 (1) 13 (7) 4 (1) - - 18 (9)
Class D1 - - - - 1 (1) 1 (1)
Class F 5 (3) 5 (1) 1 (1) - - 11 (5)
Class T2 - 16 (3) - - - 16 (3)


Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2025-01-01.


Structural coverage of GPCR-G protein complexes.


Receptor names:


Class A
(Rhodopsin)


G Protein complexes
s i/o q/11 12/13 GPa1




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)