Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 64 | 125 | 13 | 6 | - | 208 |
Receptor - G protein complexes | 135 | 134 | 17 | 3 | 1 | 290 |
Total structures | 199 | 259 | 30 | 9 | 1 | 498 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 61 (20) | 120 (49) | 17 (14) | 1 (1) | - | 199 (84) |
Class B1 | 70 (14) | 1 (1) | - | - | - | 71 (15) |
Class B2 | 3 (3) | 4 (2) | - | 2 (2) | - | 9 (7) |
Class C | - | 4 (3) | - | - | - | 4 (3) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 1 (1) | 5 (1) | - | - | - | 6 (2) |
Class T2 | - | - | - | - | - | 0 (0) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2022-07-27.
Structural coverage of GPCR-G protein complexes.
Receptor names: