Number of G protein structures

Structures Gs Gi/o Gq/11 G12/13 GPa1 Total
Non complexed G protein 36 95 9 6 - 146
Receptor - G protein complexes 85 64 10 - 1 160
Total structures 121 159 19 6 1 306


Number of GPCR-G protein structures (distinct complexes)

Receptor Class Gs Gi/o Gq/11 G12/13 GPa1 Total
Class A 40 (14) 52 (26) 10 (8) - - 102 (48)
Class B1 44 (14) 1 (1) - - - 45 (15)
Class B2 - 2 (1) - - - 2 (1)
Class C - 4 (3) - - - 4 (3)
Class D1 - - - - 1 (1) 1 (1)
Class F 1 (1) 5 (1) - - - 6 (2)
Class T2 - - - - - 0 (0)


Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2021-12-15.


Structural coverage of GPCR-G protein complexes. The five dots depict G protein complex structure presence.


Receptor names:

⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1