Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 34 | 88 | 11 | 7 | - | 140 |
Receptor - G protein complexes | 190 | 206 | 47 | 6 | 1 | 450 |
Total structures | 224 | 294 | 58 | 13 | 1 | 590 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 90 (23) | 186 (72) | 44 (22) | 1 (1) | - | 321 (118) |
Class B1 | 86 (15) | 2 (2) | 1 (1) | - | - | 89 (18) |
Class B2 | 13 (6) | 6 (3) | 2 (2) | 5 (5) | - | 26 (16) |
Class C | - | 4 (3) | - | - | - | 4 (3) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 1 (1) | 5 (1) | - | - | - | 6 (2) |
Class T2 | - | 3 (1) | - | - | - | 3 (1) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2022-12-28.
Structural coverage of GPCR-G protein complexes.
Receptor names: