CHEMBL413105


SMILES CN(C)C1CCc2ccc3[nH]ccc3c2C1
InChIKey HENBLLXAHPTGHX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 214.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.52 7.07 7.62 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.18 7.5 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 4.71 4.71 4.71 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 5.74 5.74 5.74 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.09 7.09 7.09 ChEMBL