CHEMBL427013


SMILES COC1(C#CC(O)(c2ccccc2)c2ccc(F)nc2)CN2CCC1CC2
InChIKey NHSNVFUDXZEPFP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.49 9.49 9.49 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database