CHEMBL4468100


SMILES CCCC(C)(C)C(=O)N(CC)CCCC1CCN(CC(=O)N2c3ccc(Cl)cc3C(=O)Nc3cccnc32)CC1
InChIKey LUPAFPUKESJDMZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 567.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.84 5.84 5.84 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.76 6.76 6.76 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.11 6.11 6.11 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.52 7.52 7.52 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database