CHEMBL451394


SMILES O=C(Nc1ccc2[nH]cc(C3CCN(Cc4cccc(CN5CCC(c6c[nH]c7ccc(NC(=O)c8ccc(F)cc8)cc67)CC5)c4)CC3)c2c1)c1ccc(F)cc1
InChIKey FYMYEYOPWYBNKY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 10
Molecular weight (Da) 776.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 PDSP Ki database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database