CHEMBL4594879


SMILES Cc1nc(N)[nH]c1-c1cn(S(=O)(=O)c2cccc3ccccc23)c2ccccc12
InChIKey OEXOYPPMGZXWRP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 402.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.93 5.93 5.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database