CHEMBL4650652


SMILES NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey QOJBMAYEUGMTTA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 518.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.63 6.63 6.63 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 9.35 9.35 9.35 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.84 6.84 6.84 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.74 9.74 9.74 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.23 8.74 9.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database