CHEMBL1277565


SMILES Cn1nc(S(=O)(=O)c2cccc3ccccc23)c2cc(N3CCNCC3)ccc21
InChIKey IKUNVINCAHHDMJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 406.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.56 5.56 5.56 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.65 5.65 5.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.8 8.8 8.8 ChEMBL