CHEMBL493305


SMILES CSc1ccccc1N1CCN(CCCCCC(=O)N2CCc3ccccc3C2)CC1
InChIKey XAAGODSBJUUWCQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 437.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.69 8.69 8.69 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.4 7.4 7.4 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.69 8.69 8.69 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database