CHEMBL494316


SMILES COc1ccccc1N1CCN(CCCCCC(=O)N2Cc3ccccc3C2)CC1
InChIKey OMGFHJJVBNGXBW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 407.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.49 8.49 8.49 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.49 8.49 8.49 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.14 6.14 6.14 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database