CHEMBL4787498


SMILES CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc(CN3CCC4(CCc5ccccc54)CC3)s2)cc1
InChIKey LGIUHWQDGPFXSG-VWLOTQADSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 499.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pKi 8.09 8.09 8.09 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pKd 8.46 8.46 8.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Mouse Free fatty acid A pEC50 8.92 8.92 8.92 ChEMBL
FFA1 FFAR1 Rat Free fatty acid A pEC50 8.77 8.77 8.77 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pEC50 8.1 8.14 8.21 ChEMBL