CHEMBL5186821


SMILES Nc1nc(N)nc(NCCCCN2CCN(c3ccccc3)CC2)n1
InChIKey LKJCFVNDNPLBSN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 342.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.76 4.76 4.76 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.25 7.25 7.25 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.58 5.58 5.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database