CHEMBL5201984


SMILES O=c1n(CCCCCCN2CCN(c3cccc(Cl)c3)CC2)c2cccc3c2n1CCC3
InChIKey GHLSRSRUPDWWMF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.21 7.21 7.21 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.94 5.94 5.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.18 7.18 7.18 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database