CHEMBL196370


SMILES COc1ccc(NC(=O)N2CCN(c3ccccc3OC)CC2)cc1N1CCN(C)CC1
InChIKey FBDANPRMCCLYRK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 439.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.91 8.44 8.7 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.97 7.01 7.05 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.16 6.18 6.19 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database