CHEMBL2031737


SMILES C[C@@H]1CCCN1CCc1cc2cc(C(=O)c3ccc([N+](=O)[O-])cc3)ccc2o1
InChIKey GPZMWOXSIRVXQW-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.28 5.28 5.28 ChEMBL
H2 HRH2 Human Histamine A pKi 6.04 6.04 6.04 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.47 6.47 6.47 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.38 6.38 6.38 ChEMBL
H1 HRH1 Human Histamine A pKi 5.15 5.15 5.15 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.29 6.29 6.29 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.17 6.17 6.17 ChEMBL
H3 HRH3 Human Histamine A pKi 9.4 9.4 9.4 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.03 6.03 6.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database