CHEMBL2112957


SMILES O=C(NC[C@H]1CCCN(CC2CCCCC2)C1)[C@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1
InChIKey UCBXWLPRAVDTBU-UZNICKRLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 688.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.82 6.82 6.82 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.64 8.64 8.64 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.6 9.6 9.6 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.09 9.09 9.09 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.85 7.85 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database