CHEMBL215180


SMILES O=C(NCC1CCNCC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1
InChIKey CNPFYHSXAKKLOF-SLGZMBILSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 662.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKd 9.65 9.65 9.65 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKd 6.69 6.69 6.69 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.46 5.46 5.46 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.38 7.38 7.38 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.5 9.51 9.52 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.31 6.31 6.31 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.77 6.77 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database