CHEMBL2205812


SMILES COc1ccc(CCN2C3C4C5CC6C7C5C3C7C2(O)C64)cc1
InChIKey TWMXGXSGGIIQDM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 5.77 5.77 5.77 ChEMBL
H2 HRH2 Human Histamine A pKi 6.4 6.4 6.4 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.77 5.77 5.77 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.33 6.33 6.33 ChEMBL
H1 HRH1 Human Histamine A pKi 5.42 5.42 5.42 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.39 6.39 6.39 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.67 6.67 6.67 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.5 7.5 7.5 ChEMBL
κ OPRK Human Opioid A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database