CHEMBL257744


SMILES COc1c(Cl)ccc2c1C(C)NC(NCC(F)F)=N2
InChIKey PZVDYPMNMHJRDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 289.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.65 7.65 7.65 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database