adrb1_melga
NAME
6H7J
ORGANISM
Wild turkey (Meleagris gallopavo)
PROTEIN NAME
adrb1_melga
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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G
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D
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G
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W
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L
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P
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P
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D
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C
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10 |
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|
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G
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P
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H
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N
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R
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S
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G
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G
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G
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G
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20 |
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|
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A
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T
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A
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A
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P
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T
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G
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S
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R
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Q
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30 |
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TM1 | |||||||||
V
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S
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A
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E
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L
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L
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S
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Q
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Q
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W
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40 |
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|||||||
E
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A
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G
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M
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S
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L
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L
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M
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A
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L
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50 |
V
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V
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L
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L
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I
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V
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A
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G
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N
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V
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60 |
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|||||||||
L
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V
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I
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A
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A
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I
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G
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R
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T
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Q
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70 |
ICL1 | TM2 | ||||||||
R
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L
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Q
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T
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L
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T
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N
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L
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F
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I
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80 |
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|||||||||
T
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S
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L
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A
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C
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A
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D
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L
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V
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M
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90 |
G
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L
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L
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V
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V
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P
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F
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G
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A
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T
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100 |
ECL1 | |||||||||
L
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V
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V
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R
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G
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T
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W
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L
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W
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G
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110 |
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|||||||||
TM3 | |||||||||
S
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F
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L
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C
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E
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C
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W
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T
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S
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L
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120 |
D
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V
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L
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C
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V
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T
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A
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S
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I
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E
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130 |
T
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L
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C
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V
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I
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A
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I
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D
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R
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Y
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140 |
ICL2 | |||||||||
L
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A
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I
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T
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S
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P
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F
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R
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Y
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Q
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150 |
TM4 | |||||||||
S
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L
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M
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T
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R
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A
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R
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A
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K
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V
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160 |
I
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I
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C
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T
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V
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W
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A
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I
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S
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A
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170 |
L
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V
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S
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F
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L
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P
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I
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M
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M
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H
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180 |
ECL2 | |||||||||
W
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W
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R
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D
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E
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D
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P
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Q
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A
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L
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190 |
K
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C
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Y
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Q
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D
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P
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G
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C
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C
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D
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200 |
TM5 | |||||||||
F
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V
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T
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N
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R
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A
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Y
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A
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I
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A
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210 |
S
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S
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I
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I
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S
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F
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Y
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I
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P
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L
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220 |
L
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I
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M
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I
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F
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V
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Y
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L
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R
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V
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230 |
Y
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R
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E
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A
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K
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E
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Q
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I
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R
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K
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240 |
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ICL3 | |||||||||
I
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D
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R
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C
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E
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G
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R
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F
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Y
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G
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250 |
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S
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Q
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E
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Q
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P
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Q
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P
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P
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P
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L
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260 |
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|
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P
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Q
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H
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Q
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P
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I
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L
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G
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N
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G
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270 |
TM6 | |||||||||
R
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A
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S
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K
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R
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K
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T
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S
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R
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V
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280 |
M
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A
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M
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R
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E
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H
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K
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A
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L
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K
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290 |
T
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L
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G
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I
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I
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M
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G
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V
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F
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T
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300 |
L
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C
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W
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L
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P
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F
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F
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L
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V
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N
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310 |
ECL3 | |||||||||
I
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V
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N
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V
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F
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N
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R
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D
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L
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V
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320 |
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|||||||||
TM7 | |||||||||
P
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D
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W
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L
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F
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V
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F
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F
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N
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W
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330 |
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|||||||||
L
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G
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Y
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A
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N
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S
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A
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F
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N
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P
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340 |
H8 | |||||||||
I
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I
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Y
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C
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R
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S
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P
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D
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F
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R
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350 |
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|||||||||
K
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A
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F
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K
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R
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L
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L
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C
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F
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P
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360 |
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||||||||
C-term | |||||||||
R
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K
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A
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D
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R
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R
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L
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H
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A
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G
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370 |
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|
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G
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Q
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P
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A
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P
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L
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P
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G
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G
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F
|
380 |
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|
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I
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S
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T
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L
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G
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S
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P
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E
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H
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S
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390 |
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|
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P
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G
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G
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T
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W
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S
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D
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C
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N
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G
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400 |
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|
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G
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T
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R
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G
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G
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S
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E
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S
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S
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L
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410 |
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|
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|
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E
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E
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R
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H
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S
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K
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T
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S
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R
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S
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420 |
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|
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E
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S
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K
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M
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E
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R
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E
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K
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N
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I
|
430 |
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L
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A
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T
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T
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R
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F
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Y
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C
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T
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F
|
440 |
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|
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L
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G
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N
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G
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D
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K
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A
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V
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F
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C
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450 |
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T
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V
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L
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R
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I
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V
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K
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L
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F
|
E
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460 |
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|
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D
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A
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T
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C
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T
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C
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P
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H
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T
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H
|
470 |
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|
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K
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L
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K
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M
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K
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W
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R
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F
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K
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Q
|
480 |
|
|
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H
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Q
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A
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|||||||||
TM1 | |||||||||
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M
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S
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L
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L
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M
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A
|
L
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V
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V
|
52 |
L
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L
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I
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V
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A
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G
|
N
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V
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L
|
V
|
62 |
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|||||||||
I
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A
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A
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I
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G
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S
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T
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Q
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R
|
L
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72 |
ICL1 | TM2 | ||||||||
Q
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T
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L
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T
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N
|
L
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F
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I
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T
|
S
|
82 |
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|||||||||
L
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A
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C
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A
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D
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L
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V
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V
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G
|
L
|
92 |
L
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V
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V
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P
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F
|
G
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A
|
T
|
L
|
V
|
102 |
ECL1 | TM3 | ||||||||
V
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R
|
G
|
T
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W
|
L
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W
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G
|
S
|
F
|
112 |
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|||||||||
L
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C
|
E
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L
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W
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T
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S
|
L
|
D
|
V
|
122 |
L
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C
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V
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T
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A
|
S
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I
|
E
|
T
|
L
|
132 |
C
|
V
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I
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A
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I
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D
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R
|
Y
|
L
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A
|
142 |
ICL2 | |||||||||
I
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T
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S
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P
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F
|
R
|
Y
|
Q
|
S
|
L
|
152 |
TM4 | |||||||||
M
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T
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R
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A
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R
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A
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K
|
V
|
I
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I
|
162 |
C
|
T
|
V
|
W
|
A
|
I
|
S
|
A
|
L
|
V
|
172 |
S
|
F
|
L
|
P
|
I
|
M
|
M
|
H
|
W
|
W
|
182 |
ECL2 | |||||||||
R
|
D
|
E
|
D
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P
|
Q
|
A
|
L
|
K
|
C
|
192 |
Y
|
Q
|
D
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P
|
G
|
C
|
C
|
D
|
F
|
V
|
202 |
TM5 | |||||||||
T
|
N
|
R
|
A
|
Y
|
A
|
I
|
A
|
S
|
S
|
212 |
I
|
I
|
S
|
F
|
Y
|
I
|
P
|
L
|
L
|
I
|
222 |
M
|
I
|
F
|
V
|
Y
|
L
|
R
|
V
|
Y
|
R
|
232 |
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|||||||||||||||||||||||||||||||||||||||
ICL3 | TM6 | ||||||||||||||||||||||||||||||||||||||
E
|
A
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K
|
E
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Q
|
I
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R
|
K
|
I
|
D
|
|
R
|
A
|
S
|
K
|
R
|
K
|
T
|
S
|
R
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||||||||||||||||||||
242 | 279 |
V
|
M
|
A
|
M
|
R
|
E
|
H
|
K
|
A
|
L
|
289 |
K
|
T
|
L
|
G
|
I
|
I
|
M
|
G
|
V
|
F
|
299 |
T
|
L
|
C
|
W
|
L
|
P
|
F
|
F
|
L
|
V
|
309 |
N
|
I
|
V
|
N
|
V
|
F
|
N
|
R
|
D
|
L
|
319 |
|
|||||||||
ECL3 | TM7 | ||||||||
V
|
P
|
D
|
W
|
L
|
F
|
V
|
A
|
F
|
N
|
329 |
|
|||||||||
W
|
L
|
G
|
Y
|
A
|
N
|
S
|
A
|
M
|
N
|
339 |
H8 | |||||||||
P
|
I
|
I
|
Y
|
C
|
R
|
S
|
P
|
D
|
F
|
349 |
R
|
K
|
A
|
F
|
K
|
R
|
L
|
L
|
357 |
|
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Thioredoxin | ||||||||||
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|
|||
C
|
F
|
P
|
R
|
361 |
|
|||||||
C-term | |||||||
K
|
A
|
D
|
R
|
R
|
L
|
H
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|---|---|
68 | | R | S |
90 | | M | V |
116 | | C | L |
327 | | F | A |
338 | | F | M |
358 | | C | A |
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
Protein_type: auto
Name: Thioredoxin 1
Sequence: None
Deletions:
Positions: Within Receptor_0 358:358
Presence in Crystal:YES
Remarks: None
Protein_type: auto
Name: Expression tag
Sequence: None
Deletions:
Positions: Within Receptor_1 358:358
Presence in Crystal:YES
Remarks: None
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|