ada2b_human
NAME
6K42
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
ada2b_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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D
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H
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Q
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D
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P
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Y
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S
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V
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Q
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10 |
TM1 | |||||||||
A
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T
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A
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A
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I
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A
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A
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A
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I
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T
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20 |
F
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L
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I
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L
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F
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T
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I
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F
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G
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N
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30 |
A
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L
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V
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I
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L
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A
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V
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L
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T
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S
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40 |
ICL1 | TM2 | ||||||||
R
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S
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L
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R
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A
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P
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Q
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N
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L
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F
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50 |
L
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V
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S
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L
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A
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A
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A
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D
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I
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L
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60 |
V
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A
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T
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L
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I
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I
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P
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F
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S
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L
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70 |
ECL1 | |||||||||
A
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N
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E
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L
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L
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G
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Y
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W
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Y
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F
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80 |
TM3 | |||||||||
R
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R
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T
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W
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C
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E
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V
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Y
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L
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A
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90 |
L
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D
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V
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L
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F
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C
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T
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S
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S
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I
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100 |
V
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H
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L
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C
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A
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I
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S
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L
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D
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R
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110 |
ICL2 | |||||||||
Y
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W
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A
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V
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S
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R
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A
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L
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E
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Y
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120 |
TM4 | |||||||||
N
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S
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K
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R
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T
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P
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R
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R
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I
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K
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130 |
C
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I
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I
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L
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T
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V
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W
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L
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I
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A
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140 |
A
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V
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I
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S
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L
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P
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P
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L
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I
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Y
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150 |
ECL2 | |||||||||
K
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G
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D
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Q
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G
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P
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Q
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P
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R
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G
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160 |
R
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P
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Q
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C
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K
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L
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N
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Q
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E
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A
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170 |
TM5 | |||||||||
W
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Y
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I
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L
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A
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S
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S
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I
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G
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S
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180 |
F
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F
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A
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P
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C
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L
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I
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M
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I
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L
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190 |
V
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Y
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L
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R
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I
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Y
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L
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I
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A
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K
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200 |
R
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S
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N
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R
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R
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G
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P
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R
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A
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K
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210 |
|
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|||||||
ICL3 | |||||||||
G
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G
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P
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G
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Q
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G
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E
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S
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K
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Q
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220 |
|
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P
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R
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P
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D
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H
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G
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G
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A
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L
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A
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230 |
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|
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S
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A
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K
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L
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P
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A
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L
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A
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S
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V
|
240 |
|
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A
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S
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A
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R
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E
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V
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N
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G
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H
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S
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250 |
|
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|
|
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K
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S
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T
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G
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E
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K
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E
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E
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G
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E
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260 |
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T
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P
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E
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D
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T
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G
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T
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R
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A
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L
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270 |
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|
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P
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P
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S
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W
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A
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A
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L
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P
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N
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S
|
280 |
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|
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G
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Q
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G
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Q
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K
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E
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G
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V
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C
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G
|
290 |
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|
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A
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S
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P
|
E
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D
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E
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A
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E
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E
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E
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300 |
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E
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E
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E
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E
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E
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E
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E
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E
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E
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C
|
310 |
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|
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E
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P
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Q
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A
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V
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P
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V
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S
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P
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A
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320 |
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|
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S
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A
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C
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S
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P
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P
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L
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Q
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Q
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P
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330 |
|
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|
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Q
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G
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S
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R
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V
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L
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A
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T
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L
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R
|
340 |
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|
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|
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G
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Q
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V
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L
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L
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G
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R
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G
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V
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G
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350 |
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||||||
A
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I
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G
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G
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Q
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W
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W
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R
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R
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R
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360 |
TM6 | |||||||||
A
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Q
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L
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T
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R
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E
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K
|
R
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F
|
T
|
370 |
F
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V
|
L
|
A
|
V
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V
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I
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G
|
V
|
F
|
380 |
V
|
L
|
C
|
W
|
F
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P
|
F
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F
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F
|
S
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390 |
Y
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S
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L
|
G
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A
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I
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C
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P
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K
|
H
|
400 |
ECL3 | TM7 | ||||||||
C
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K
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V
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P
|
H
|
G
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L
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F
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Q
|
F
|
410 |
F
|
F
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W
|
I
|
G
|
Y
|
C
|
N
|
S
|
S
|
420 |
L
|
N
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P
|
V
|
I
|
Y
|
T
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I
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F
|
N
|
430 |
H8 | |||||||||
Q
|
D
|
F
|
R
|
R
|
A
|
F
|
R
|
R
|
I
|
440 |
C-term | |||||||||
L
|
C
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R
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P
|
W
|
T
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Q
|
T
|
A
|
W
|
450 |
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|||||||||
N-term | TM1 | ||||||||
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Y
|
S
|
V
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Q
|
A
|
T
|
A
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A
|
I
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15 |
A
|
A
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A
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I
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T
|
F
|
L
|
I
|
L
|
F
|
25 |
T
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I
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F
|
G
|
N
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A
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L
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V
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I
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L
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35 |
ICL1 | |||||||||
A
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V
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L
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T
|
S
|
R
|
S
|
L
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R
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A
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45 |
TM2 | |||||||||
P
|
Q
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N
|
L
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F
|
L
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V
|
S
|
L
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A
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55 |
A
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A
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D
|
I
|
L
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V
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A
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T
|
L
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I
|
65 |
I
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P
|
F
|
S
|
L
|
A
|
N
|
E
|
L
|
L
|
75 |
ECL1 | TM3 | ||||||||
G
|
Y
|
W
|
Y
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F
|
R
|
R
|
T
|
W
|
C
|
85 |
E
|
V
|
Y
|
L
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A
|
L
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D
|
V
|
L
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F
|
95 |
C
|
T
|
S
|
S
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I
|
V
|
H
|
L
|
C
|
A
|
105 |
I
|
S
|
L
|
D
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R
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Y
|
W
|
A
|
V
|
S
|
115 |
ICL2 | |||||||||
R
|
A
|
L
|
E
|
Y
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N
|
S
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K
|
R
|
T
|
125 |
TM4 | |||||||||
P
|
R
|
R
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I
|
K
|
C
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I
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I
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L
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T
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135 |
V
|
W
|
L
|
I
|
A
|
A
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V
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I
|
S
|
L
|
145 |
ECL2 | |||||||||
P
|
P
|
L
|
I
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Y
|
K
|
G
|
D
|
Q
|
G
|
155 |
P
|
Q
|
P
|
R
|
G
|
R
|
P
|
Q
|
C
|
K
|
165 |
TM5 | |||||||||
L
|
N
|
Q
|
E
|
A
|
W
|
Y
|
I
|
L
|
A
|
175 |
S
|
S
|
I
|
G
|
S
|
F
|
F
|
A
|
P
|
C
|
185 |
L
|
I
|
M
|
I
|
L
|
V
|
Y
|
L
|
R
|
I
|
195 |
Y
|
L
|
I
|
A
|
K
|
R
|
S
|
N
|
R
|
R
|
205 |
ICL3 | |||||||||
G
|
P
|
R
|
A
|
K
|
G
|
G
|
P
|
G
|
Q
|
215 |
|
|||||||||
G
|
E
|
|
Q
|
W
|
W
|
R
|
R
|
R
|
A
|
361 |
TM6 | |||||||||
Q
|
L
|
T
|
R
|
E
|
K
|
R
|
F
|
T
|
F
|
371 |
V
|
L
|
A
|
V
|
V
|
I
|
G
|
V
|
F
|
V
|
381 |
L
|
C
|
W
|
F
|
P
|
F
|
F
|
F
|
S
|
Y
|
391 |
ECL3 | |||||||||
S
|
L
|
G
|
A
|
I
|
C
|
P
|
K
|
H
|
C
|
401 |
TM7 | |||||||||
K
|
V
|
P
|
H
|
G
|
L
|
F
|
Q
|
F
|
F
|
411 |
F
|
W
|
I
|
G
|
Y
|
C
|
N
|
S
|
S
|
L
|
421 |
H8 | |||||||||
N
|
P
|
V
|
I
|
Y
|
T
|
I
|
F
|
N
|
Q
|
431 |
D
|
F
|
R
|
R
|
A
|
F
|
R
|
R
|
I
|
L
|
441 |
C-term | ||||||||
C
|
R
|
P
|
W
|
T
|
Q
|
T
|
A
|
W
|
450 |
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|