ada2a_human
NAME
6KUX
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
ada2a_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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F
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R
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Q
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E
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Q
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P
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L
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A
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E
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10 |
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G
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S
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F
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A
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P
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M
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G
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S
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L
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Q
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20 |
P
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D
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A
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G
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N
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A
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S
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W
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N
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G
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30 |
T
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E
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A
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P
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G
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G
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G
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A
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R
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A
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40 |
TM1 | |||||||||
T
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P
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Y
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S
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L
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Q
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V
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T
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L
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T
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50 |
L
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V
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C
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L
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A
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G
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L
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L
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M
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L
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60 |
L
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T
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V
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F
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G
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N
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V
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L
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V
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I
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70 |
ICL1 | |||||||||
I
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A
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V
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F
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T
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S
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R
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A
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L
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K
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80 |
TM2 | |||||||||
A
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P
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Q
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N
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L
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F
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L
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V
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S
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L
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90 |
A
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S
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A
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D
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T
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L
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100 |
V
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I
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P
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F
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S
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L
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A
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N
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E
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V
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110 |
ECL1 | TM3 | ||||||||
M
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G
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Y
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W
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Y
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F
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G
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K
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A
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W
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120 |
C
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E
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I
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Y
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L
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A
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L
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D
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V
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L
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130 |
F
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C
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T
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S
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S
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I
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V
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H
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L
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C
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140 |
A
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I
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S
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L
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D
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R
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Y
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W
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S
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I
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150 |
ICL2 | |||||||||
T
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Q
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A
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I
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E
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Y
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N
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L
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K
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R
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160 |
TM4 | |||||||||
T
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P
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R
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R
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I
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K
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A
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I
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I
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I
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170 |
T
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V
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W
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V
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I
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S
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A
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V
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I
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S
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180 |
ECL2 | |||||||||
F
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P
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P
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L
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I
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S
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I
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E
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K
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K
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190 |
G
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G
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G
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G
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G
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P
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Q
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P
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A
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E
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200 |
TM5 | |||||||||
P
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R
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C
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E
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I
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N
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D
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Q
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K
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W
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210 |
Y
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V
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I
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S
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S
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C
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I
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G
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S
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F
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220 |
F
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A
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P
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C
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L
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I
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M
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I
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L
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V
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230 |
Y
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V
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R
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I
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Y
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Q
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I
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A
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K
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R
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240 |
R
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T
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R
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V
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P
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P
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S
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R
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R
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G
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250 |
ICL3 | |||||||||
P
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D
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A
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V
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A
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A
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P
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P
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G
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G
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260 |
T
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E
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R
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R
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P
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N
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G
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L
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G
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P
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270 |
E
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R
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S
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A
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G
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P
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G
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G
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A
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280 |
A
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E
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P
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L
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P
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T
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Q
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L
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N
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G
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290 |
A
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P
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P
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A
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A
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P
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300 |
R
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D
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D
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A
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L
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D
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L
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E
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E
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310 |
S
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S
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S
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S
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D
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H
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A
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R
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P
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320 |
P
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R
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P
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330 |
R
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K
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G
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K
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A
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A
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Q
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340 |
V
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K
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L
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R
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350 |
G
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P
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G
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A
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T
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G
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I
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G
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T
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P
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360 |
A
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A
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P
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G
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E
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E
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R
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V
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G
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370 |
TM6 | |||||||||
A
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A
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K
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A
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S
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R
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W
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R
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G
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R
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380 |
Q
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N
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R
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E
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K
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R
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F
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T
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F
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V
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390 |
L
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A
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V
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V
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I
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G
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V
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F
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V
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V
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400 |
C
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W
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F
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P
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F
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F
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F
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T
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Y
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T
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410 |
ECL3 | |||||||||
L
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T
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A
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V
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G
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C
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S
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V
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P
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R
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420 |
TM7 | |||||||||
T
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L
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F
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K
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F
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F
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F
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W
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F
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G
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430 |
Y
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C
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N
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S
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S
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L
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N
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P
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V
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I
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440 |
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H8 | |||||||||
Y
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T
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I
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F
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N
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H
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D
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F
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R
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R
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450 |
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A
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F
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K
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K
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I
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L
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C
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R
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G
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D
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460 |
|
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C-term | |||||
R
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K
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R
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I
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V
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|||||||||
N-term | |||||||||
|
Q
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P
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D
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A
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G
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N
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A
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S
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W
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28 |
N
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G
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T
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E
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A
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P
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G
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G
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G
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A
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38 |
TM1 | |||||||||
R
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A
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T
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P
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Y
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S
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L
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Q
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V
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T
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48 |
L
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T
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L
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V
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C
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L
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A
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G
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L
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L
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58 |
M
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L
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L
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T
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V
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F
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G
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N
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V
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L
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68 |
V
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I
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I
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A
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V
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F
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T
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S
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R
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A
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78 |
ICL1 | TM2 | ||||||||
L
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K
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A
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P
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Q
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N
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L
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F
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L
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V
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88 |
S
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L
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A
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S
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A
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D
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I
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L
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V
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A
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98 |
T
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L
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V
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I
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P
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F
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S
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L
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A
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N
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108 |
ECL1 | |||||||||
E
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V
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M
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G
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Y
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W
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Y
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F
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G
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K
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118 |
TM3 | |||||||||
A
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W
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C
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E
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I
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Y
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L
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A
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L
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D
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128 |
V
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L
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F
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C
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T
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S
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S
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I
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V
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H
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138 |
L
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C
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A
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I
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S
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L
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D
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R
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Y
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W
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148 |
ICL2 | |||||||||
S
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I
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T
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Q
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A
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I
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E
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Y
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N
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L
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158 |
TM4 | |||||||||
K
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R
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T
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P
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R
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R
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I
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K
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A
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I
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168 |
I
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I
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T
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V
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W
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V
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I
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S
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A
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V
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178 |
I
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S
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F
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P
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P
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L
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I
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S
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I
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E
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188 |
ECL2 | |||||||||
K
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K
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G
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G
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G
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G
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G
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P
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Q
|
P
|
198 |
A
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E
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P
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R
|
C
|
E
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I
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N
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D
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Q
|
208 |
TM5 | |||||||||
K
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W
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Y
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V
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I
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S
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S
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C
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I
|
G
|
218 |
S
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F
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F
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A
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P
|
C
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L
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I
|
M
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I
|
228 |
L
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V
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Y
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V
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R
|
I
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Y
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Q
|
I
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A
|
238 |
K
|
R
|
R
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T
|
R
|
V
|
P
|
P
|
S
|
R
|
248 |
ICL3 | |||||||||
R
|
G
|
P
|
D
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A
|
V
|
A
|
A
|
P
|
P
|
258 |
G
|
G
|
T
|
E
|
R
|
R
|
P
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N
|
G
|
L
|
268 |
G
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P
|
E
|
R
|
S
|
A
|
G
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P
|
G
|
G
|
278 |
A
|
E
|
A
|
E
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P
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L
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P
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T
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Q
|
L
|
288 |
N
|
G
|
A
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P
|
G
|
E
|
P
|
A
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P
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A
|
298 |
G
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P
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R
|
D
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T
|
D
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A
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L
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D
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L
|
308 |
E
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E
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S
|
S
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S
|
S
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D
|
H
|
A
|
E
|
318 |
R
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P
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P
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G
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P
|
R
|
R
|
P
|
E
|
R
|
328 |
G
|
P
|
R
|
G
|
K
|
G
|
K
|
A
|
R
|
A
|
338 |
S
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Q
|
V
|
K
|
P
|
G
|
D
|
S
|
L
|
P
|
348 |
R
|
R
|
G
|
P
|
G
|
A
|
T
|
G
|
I
|
G
|
358 |
T
|
P
|
A
|
A
|
G
|
P
|
G
|
E
|
E
|
R
|
368 |
V
|
G
|
A
|
A
|
K
|
A
|
S
|
R
|
W
|
R
|
378 |
TM6 | |||||||||
G
|
R
|
Q
|
N
|
R
|
E
|
K
|
R
|
F
|
T
|
388 |
F
|
V
|
L
|
A
|
V
|
V
|
I
|
G
|
V
|
F
|
398 |
V
|
V
|
C
|
W
|
F
|
P
|
F
|
F
|
F
|
T
|
408 |
Y
|
T
|
L
|
T
|
A
|
V
|
G
|
C
|
S
|
V
|
418 |
TM7 | |||||||||
P
|
R
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T
|
L
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F
|
K
|
F
|
F
|
F
|
W
|
428 |
F
|
G
|
Y
|
C
|
N
|
S
|
S
|
L
|
N
|
P
|
438 |
|
|||||||
H8 | |||||||
V
|
I
|
Y
|
T
|
I
|
F
|
N
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|