ntr1_human
NAME
6OS9
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
ntr1_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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R
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L
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N
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S
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S
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A
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P
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G
|
T
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10 |
|
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|
|
|
|
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|
|
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P
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G
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T
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P
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A
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A
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D
|
P
|
F
|
Q
|
20 |
R
|
A
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Q
|
A
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G
|
L
|
E
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E
|
A
|
L
|
30 |
L
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A
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P
|
G
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F
|
G
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N
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A
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S
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G
|
40 |
N
|
A
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S
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E
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R
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V
|
L
|
A
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A
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P
|
50 |
S
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S
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E
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L
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D
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V
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N
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T
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D
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I
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60 |
TM1 | |||||||||
Y
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S
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K
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V
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L
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V
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T
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A
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V
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Y
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70 |
L
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A
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L
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F
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V
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V
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G
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T
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V
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G
|
80 |
N
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T
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V
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T
|
A
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F
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T
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L
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A
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R
|
90 |
ICL1 | TM2 | ||||||||
K
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K
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S
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L
|
Q
|
S
|
L
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Q
|
S
|
T
|
100 |
V
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H
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Y
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H
|
L
|
G
|
S
|
L
|
A
|
L
|
110 |
S
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D
|
L
|
L
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T
|
L
|
L
|
L
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A
|
M
|
120 |
P
|
V
|
E
|
L
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Y
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N
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F
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I
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W
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V
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130 |
ECL1 | TM3 | ||||||||
H
|
H
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P
|
W
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A
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F
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G
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D
|
A
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G
|
140 |
C
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R
|
G
|
Y
|
Y
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F
|
L
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R
|
D
|
A
|
150 |
C
|
T
|
Y
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A
|
T
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A
|
L
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N
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V
|
A
|
160 |
S
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L
|
S
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V
|
E
|
R
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Y
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L
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A
|
I
|
170 |
ICL2 | |||||||||
C
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H
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P
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F
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K
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A
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K
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T
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L
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M
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180 |
TM4 | |||||||||
S
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R
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S
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R
|
T
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K
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K
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F
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I
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S
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190 |
A
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I
|
W
|
L
|
A
|
S
|
A
|
L
|
L
|
A
|
200 |
V
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P
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M
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L
|
F
|
T
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M
|
G
|
E
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Q
|
210 |
ECL2 | |||||||||
N
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R
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S
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A
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D
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G
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Q
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H
|
A
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G
|
220 |
G
|
L
|
V
|
C
|
T
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P
|
T
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I
|
H
|
T
|
230 |
TM5 | |||||||||
A
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T
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V
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K
|
V
|
V
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I
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Q
|
V
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N
|
240 |
T
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F
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M
|
S
|
F
|
I
|
F
|
P
|
M
|
V
|
250 |
V
|
I
|
S
|
V
|
L
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N
|
T
|
I
|
I
|
A
|
260 |
N
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K
|
L
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T
|
V
|
M
|
V
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R
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Q
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A
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270 |
ICL3 | |||||||||
A
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E
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Q
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G
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Q
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V
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C
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T
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V
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G
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280 |
|
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|
|
|
|
|
|
|
|
G
|
E
|
H
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S
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T
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F
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S
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M
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A
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I
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290 |
|
|||||||||
TM6 | |||||||||
E
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P
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G
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R
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V
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Q
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A
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L
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R
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H
|
300 |
G
|
V
|
R
|
V
|
L
|
R
|
A
|
V
|
V
|
I
|
310 |
A
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F
|
V
|
V
|
C
|
W
|
L
|
P
|
Y
|
H
|
320 |
V
|
R
|
R
|
L
|
M
|
F
|
C
|
Y
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I
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S
|
330 |
ECL3 | TM7 | ||||||||
D
|
E
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Q
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W
|
T
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P
|
F
|
L
|
Y
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D
|
340 |
F
|
Y
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H
|
Y
|
F
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Y
|
M
|
V
|
T
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N
|
350 |
A
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L
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F
|
Y
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V
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S
|
S
|
T
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I
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N
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360 |
H8 | |||||||||
P
|
I
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L
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Y
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N
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L
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V
|
S
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A
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N
|
370 |
F
|
R
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H
|
I
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F
|
L
|
A
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T
|
L
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A
|
380 |
C-term | |||||||||
C
|
L
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C
|
P
|
V
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W
|
R
|
R
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R
|
R
|
390 |
K
|
R
|
P
|
A
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F
|
S
|
R
|
K
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A
|
D
|
400 |
S
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V
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S
|
S
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N
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H
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T
|
L
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S
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S
|
410 |
N
|
A
|
T
|
R
|
E
|
T
|
L
|
Y
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Expression | ||||||||||
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|||||||||
N-term | |||||||||
|
Q
|
R
|
A
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Q
|
A
|
G
|
L
|
E
|
E
|
28 |
A
|
L
|
L
|
A
|
P
|
G
|
F
|
G
|
N
|
A
|
38 |
S
|
G
|
N
|
A
|
S
|
E
|
R
|
V
|
L
|
A
|
48 |
A
|
P
|
S
|
S
|
E
|
L
|
D
|
V
|
N
|
T
|
58 |
TM1 | |||||||||
D
|
I
|
Y
|
S
|
K
|
V
|
L
|
V
|
T
|
A
|
68 |
V
|
Y
|
L
|
A
|
L
|
F
|
V
|
V
|
G
|
T
|
78 |
V
|
G
|
N
|
T
|
V
|
T
|
A
|
F
|
T
|
L
|
88 |
ICL1 | TM2 | ||||||||
A
|
R
|
K
|
K
|
S
|
L
|
Q
|
S
|
L
|
Q
|
98 |
S
|
T
|
V
|
H
|
Y
|
H
|
L
|
G
|
S
|
L
|
108 |
A
|
L
|
S
|
D
|
L
|
L
|
T
|
L
|
L
|
L
|
118 |
A
|
M
|
P
|
V
|
E
|
L
|
Y
|
N
|
F
|
I
|
128 |
ECL1 | |||||||||
W
|
V
|
H
|
H
|
P
|
W
|
A
|
F
|
G
|
D
|
138 |
TM3 | |||||||||
A
|
G
|
C
|
R
|
G
|
Y
|
Y
|
F
|
L
|
R
|
148 |
D
|
A
|
C
|
T
|
Y
|
A
|
T
|
A
|
L
|
N
|
158 |
V
|
A
|
S
|
L
|
S
|
V
|
E
|
R
|
Y
|
L
|
168 |
ICL2 | |||||||||
A
|
I
|
C
|
H
|
P
|
F
|
K
|
A
|
K
|
T
|
178 |
TM4 | |||||||||
L
|
M
|
S
|
R
|
S
|
R
|
T
|
K
|
K
|
F
|
188 |
I
|
S
|
A
|
I
|
W
|
L
|
A
|
S
|
A
|
L
|
198 |
L
|
A
|
V
|
P
|
M
|
L
|
F
|
T
|
M
|
G
|
208 |
ECL2 | |||||||||
E
|
Q
|
N
|
R
|
S
|
A
|
D
|
G
|
Q
|
H
|
218 |
A
|
G
|
G
|
L
|
V
|
C
|
T
|
P
|
T
|
I
|
228 |
TM5 | |||||||||
H
|
T
|
A
|
T
|
V
|
K
|
V
|
V
|
I
|
Q
|
238 |
V
|
N
|
T
|
F
|
M
|
S
|
F
|
I
|
F
|
P
|
248 |
M
|
V
|
V
|
I
|
S
|
V
|
L
|
N
|
T
|
I
|
258 |
I
|
A
|
N
|
K
|
L
|
T
|
V
|
M
|
V
|
R
|
268 |
ICL3 | |||||||||
Q
|
A
|
A
|
E
|
Q
|
G
|
Q
|
V
|
C
|
T
|
278 |
|
|||||||||
TM6 | |||||||||
V
|
G
|
G
|
|
P
|
G
|
R
|
V
|
Q
|
A
|
297 |
L
|
R
|
H
|
G
|
V
|
R
|
V
|
L
|
R
|
A
|
307 |
V
|
V
|
I
|
A
|
F
|
V
|
V
|
C
|
W
|
L
|
317 |
P
|
Y
|
H
|
V
|
R
|
R
|
L
|
M
|
F
|
C
|
327 |
ECL3 | TM7 | ||||||||
Y
|
I
|
S
|
D
|
E
|
Q
|
W
|
T
|
P
|
F
|
337 |
L
|
Y
|
D
|
F
|
Y
|
H
|
Y
|
F
|
Y
|
M
|
347 |
V
|
T
|
N
|
A
|
L
|
F
|
Y
|
V
|
S
|
S
|
357 |
T
|
I
|
N
|
P
|
I
|
L
|
Y
|
N
|
L
|
V
|
367 |
H8 | |||||||||
S
|
A
|
N
|
F
|
R
|
H
|
I
|
F
|
L
|
A
|
377 |
T
|
L
|
A
|
C
|
L
|
C
|
P
|
V
|
W
|
R
|
387 |
C-term | |||||||||
R
|
R
|
R
|
K
|
R
|
P
|
A
|
F
|
S
|
R
|
397 |
K
|
A
|
D
|
S
|
V
|
S
|
S
|
N
|
H
|
T
|
407 |
L
|
S
|
S
|
N
|
A
|
T
|
R
|
E
|
T
|
L
|
417 |
Y
|
418 |
|
|
|
|
|
|
|
|
|
|
|
Expression | ||||||||||
|
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SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
Protein_type: auto
Name: Expression tag
Sequence: None
Deletions:
Positions: C-term_1 None:None
Presence in Crystal:YES
Remarks: None
Protein_type: auto
Name: Expression tag
Sequence: None
Deletions:
Positions: N-term_0 None:None
Presence in Crystal:YES
Remarks: None
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|