agrg5_human
NAME
7EQ1
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
agrg5_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | A.H4 | ||||||||
M
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D
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H
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C
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G
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A
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L
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F
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L
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C
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10 |
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|
|
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|
|
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L
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C
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L
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L
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T
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L
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Q
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N
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A
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T
|
20 |
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|
|
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T
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E
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T
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W
|
E
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E
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L
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L
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S
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Y
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30 |
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|
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M
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E
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N
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M
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Q
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V
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S
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R
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G
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R
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40 |
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A.h4h5 | A.H6 | ||||||||
S
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S
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V
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F
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S
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S
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R
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Q
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L
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H
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50 |
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|
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Q
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L
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E
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Q
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M
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L
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L
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N
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T
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S
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60 |
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A.h6s1 | B.S1 | ||||||||
F
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P
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G
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Y
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N
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L
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T
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L
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Q
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T
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70 |
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B.s1s2 | B.S2 | ||||||||
P
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T
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I
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Q
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S
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L
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A
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F
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K
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L
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80 |
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B.s2s3 | B.S3 | ||||||||
S
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C
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D
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F
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S
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G
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L
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S
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L
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T
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90 |
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B.s3s4 | |||||||||
S
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A
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T
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L
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K
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R
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V
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P
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Q
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A
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100 |
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|
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|
|
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G
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G
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Q
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H
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A
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R
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G
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Q
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H
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A
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110 |
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B.S5 | B.s5s6 | ||||||||
M
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Q
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F
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P
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A
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E
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L
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T
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R
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D
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120 |
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|
|
|
|
|
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A
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C
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K
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T
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R
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P
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R
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E
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L
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R
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130 |
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B.S6 | |||||||||
L
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I
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C
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I
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Y
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F
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S
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N
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T
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H
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140 |
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B.s6s7 | |||||||||
F
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F
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K
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D
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E
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N
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N
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S
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S
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L
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150 |
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||||
B.S7 | B.s7s8 | B.S8 | |||||||||||
L
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N
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N
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Y
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V
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L
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G
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A
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Q
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L
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||||
160 |
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B.s8s9 | |||||||||
S
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H
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G
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H
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V
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N
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N
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L
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R
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D
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170 |
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B.S9 | |||||||||
P
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V
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N
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I
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S
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F
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W
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H
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N
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Q
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180 |
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B.s9s10 | B.S10 | ||||||||||
S
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L
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E
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G
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Y
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T
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L
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T
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C
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V
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||
190 |
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F
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W
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K
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E
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G
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A
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R
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K
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Q
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P
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200 |
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B.s10s11 | B.S11 | |||||||||||
W
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G
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G
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W
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S
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P
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E
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G
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C
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R
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|||
210 |
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B.S12 | |||||||||
T
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E
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Q
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P
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S
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H
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S
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Q
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V
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L
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220 |
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B.S13 | B.GPS | ||||||||
C
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R
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C
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N
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H
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L
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T
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Y
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F
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A
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230 |
B.S14 | |||||||||
V
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L
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M
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Q
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L
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S
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P
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A
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L
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V
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240 |
TM1 | |||||||||
P
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A
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E
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L
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L
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A
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P
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L
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T
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Y
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250 |
I
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S
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L
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V
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G
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C
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S
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I
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S
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I
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260 |
V
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A
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S
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L
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I
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T
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V
|
L
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L
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H
|
270 |
ICL1 | TM2 | ||||||||
F
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H
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F
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R
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K
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Q
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S
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D
|
S
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L
|
280 |
T
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R
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I
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H
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M
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N
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L
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H
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A
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S
|
290 |
V
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L
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L
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L
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N
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I
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A
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F
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L
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L
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300 |
ECL1 | |||||||||
S
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P
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A
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F
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A
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M
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S
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P
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V
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P
|
310 |
TM3 | |||||||||
G
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S
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A
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C
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T
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A
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L
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A
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A
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A
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320 |
L
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H
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Y
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A
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L
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L
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S
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C
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L
|
T
|
330 |
W
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M
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A
|
I
|
E
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G
|
F
|
N
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L
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Y
|
340 |
ICL2 | |||||||||
L
|
L
|
L
|
G
|
R
|
V
|
Y
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N
|
I
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Y
|
350 |
TM4 | |||||||||
I
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R
|
R
|
Y
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V
|
F
|
K
|
L
|
G
|
V
|
360 |
L
|
G
|
W
|
G
|
A
|
P
|
A
|
L
|
L
|
V
|
370 |
L
|
L
|
S
|
L
|
S
|
V
|
K
|
S
|
S
|
V
|
380 |
ECL2 | |||||||||
Y
|
G
|
P
|
C
|
T
|
I
|
P
|
V
|
F
|
D
|
390 |
S
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W
|
E
|
N
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G
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T
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G
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F
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Q
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N
|
400 |
TM5 | |||||||||
M
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S
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I
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C
|
W
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V
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R
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S
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P
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V
|
410 |
V
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H
|
S
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V
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L
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V
|
M
|
G
|
Y
|
G
|
420 |
G
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L
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T
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S
|
L
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F
|
N
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L
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V
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V
|
430 |
L
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A
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W
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A
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L
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W
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T
|
L
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R
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R
|
440 |
ICL3 | |||||||||
L
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R
|
E
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R
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A
|
D
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A
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P
|
S
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V
|
450 |
TM6 | |||||||||
R
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A
|
C
|
H
|
D
|
T
|
V
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T
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V
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L
|
460 |
G
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L
|
T
|
V
|
L
|
L
|
G
|
T
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T
|
W
|
470 |
A
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L
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A
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F
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F
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S
|
F
|
G
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V
|
F
|
480 |
ECL3 | TM7 | ||||||||
L
|
L
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P
|
Q
|
L
|
F
|
L
|
F
|
T
|
I
|
490 |
L
|
N
|
S
|
L
|
Y
|
G
|
F
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F
|
L
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F
|
500 |
H8 | |||||||||
L
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W
|
F
|
C
|
S
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Q
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R
|
C
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R
|
S
|
510 |
E
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A
|
E
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A
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K
|
A
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Q
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I
|
E
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A
|
520 |
C-term | ||||||||
F
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S
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S
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S
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Q
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T
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T
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Q
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|
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||||||||||
B.GPS | B.S14 | |||||||||
|
T
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Y
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F
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A
|
V
|
L
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M
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Q
|
L
|
|
235 |
B.s14tm1 | TM1 | |||||||||
S
|
P
|
A
|
L
|
V
|
P
|
A
|
E
|
L
|
L
|
|
245 |
A
|
P
|
L
|
T
|
Y
|
I
|
S
|
L
|
V
|
G
|
255 |
C
|
S
|
I
|
S
|
I
|
V
|
A
|
S
|
L
|
I
|
265 |
T
|
V
|
L
|
L
|
H
|
F
|
H
|
F
|
R
|
K
|
275 |
ICL1 | TM2 | ||||||||
Q
|
S
|
D
|
S
|
L
|
T
|
R
|
I
|
H
|
M
|
285 |
N
|
L
|
H
|
A
|
S
|
V
|
L
|
L
|
L
|
N
|
295 |
I
|
A
|
F
|
L
|
L
|
S
|
P
|
A
|
F
|
A
|
305 |
ECL1 | TM3 | ||||||||
M
|
S
|
P
|
V
|
P
|
G
|
S
|
A
|
C
|
T
|
315 |
A
|
L
|
A
|
A
|
A
|
L
|
H
|
Y
|
A
|
L
|
325 |
L
|
S
|
C
|
L
|
T
|
W
|
M
|
A
|
I
|
E
|
335 |
G
|
F
|
N
|
L
|
Y
|
L
|
L
|
L
|
G
|
R
|
345 |
ICL2 | TM4 | ||||||||
V
|
Y
|
N
|
I
|
Y
|
I
|
R
|
R
|
Y
|
V
|
355 |
F
|
K
|
L
|
G
|
V
|
L
|
G
|
W
|
G
|
A
|
365 |
P
|
A
|
L
|
L
|
V
|
L
|
L
|
S
|
L
|
S
|
375 |
ECL2 | |||||||||
V
|
K
|
S
|
S
|
V
|
Y
|
G
|
P
|
C
|
T
|
385 |
I
|
P
|
V
|
F
|
D
|
S
|
W
|
E
|
N
|
G
|
395 |
T
|
G
|
F
|
Q
|
N
|
M
|
S
|
I
|
C
|
W
|
405 |
TM5 | |||||||||
V
|
R
|
S
|
P
|
V
|
V
|
H
|
S
|
V
|
L
|
415 |
V
|
M
|
G
|
Y
|
G
|
G
|
L
|
T
|
S
|
L
|
425 |
F
|
N
|
L
|
V
|
V
|
L
|
A
|
W
|
A
|
L
|
435 |
W
|
T
|
L
|
R
|
R
|
L
|
R
|
E
|
R
|
A
|
445 |
ICL3 | TM6 | ||||||||
D
|
A
|
P
|
S
|
V
|
R
|
A
|
C
|
H
|
D
|
455 |
T
|
V
|
T
|
V
|
L
|
G
|
L
|
T
|
V
|
L
|
465 |
L
|
G
|
T
|
T
|
W
|
A
|
L
|
A
|
F
|
F
|
475 |
ECL3 | TM7 | ||||||||
S
|
F
|
G
|
V
|
F
|
L
|
L
|
P
|
Q
|
L
|
485 |
F
|
L
|
F
|
T
|
I
|
L
|
N
|
S
|
L
|
Y
|
495 |
G
|
F
|
F
|
L
|
F
|
L
|
W
|
F
|
C
|
S
|
505 |
H8 | |||||||||
Q
|
R
|
C
|
R
|
S
|
E
|
A
|
E
|
A
|
K
|
515 |
A
|
Q
|
I
|
E
|
A
|
F
|
S
|
S
|
S
|
Q
|
525 |
C-term | |||||
T
|
T
|
Q
|
|||
528 |
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
|
|
|
|
|
DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|