oprm_mouse
NAME
7UL4
ORGANISM
Mouse (Mus musculus)
PROTEIN NAME
oprm_mouse
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
|
D
|
S
|
S
|
A
|
G
|
P
|
G
|
N
|
I
|
10 |
S
|
D
|
C
|
S
|
D
|
P
|
L
|
A
|
P
|
A
|
20 |
S
|
C
|
S
|
P
|
A
|
P
|
G
|
S
|
W
|
L
|
30 |
N
|
L
|
S
|
H
|
V
|
D
|
G
|
N
|
Q
|
S
|
40 |
D
|
P
|
C
|
G
|
P
|
N
|
R
|
T
|
G
|
L
|
50 |
G
|
G
|
S
|
H
|
S
|
L
|
C
|
P
|
Q
|
T
|
60 |
TM1 | |||||||||
G
|
S
|
P
|
S
|
M
|
V
|
T
|
A
|
I
|
T
|
70 |
I
|
M
|
A
|
L
|
Y
|
S
|
I
|
V
|
C
|
V
|
80 |
V
|
G
|
L
|
F
|
G
|
N
|
F
|
L
|
V
|
M
|
90 |
ICL1 | |||||||||
Y
|
V
|
I
|
V
|
R
|
Y
|
T
|
K
|
M
|
K
|
100 |
TM2 | |||||||||
T
|
A
|
T
|
N
|
I
|
Y
|
I
|
F
|
N
|
L
|
110 |
A
|
L
|
A
|
D
|
A
|
L
|
A
|
T
|
S
|
T
|
120 |
L
|
P
|
F
|
Q
|
S
|
V
|
N
|
Y
|
L
|
M
|
130 |
ECL1 | TM3 | ||||||||
G
|
T
|
W
|
P
|
F
|
G
|
N
|
I
|
L
|
C
|
140 |
K
|
I
|
V
|
I
|
S
|
I
|
D
|
Y
|
Y
|
N
|
150 |
M
|
F
|
T
|
S
|
I
|
F
|
T
|
L
|
C
|
T
|
160 |
M
|
S
|
V
|
D
|
R
|
Y
|
I
|
A
|
V
|
C
|
170 |
ICL2 | |||||||||
H
|
P
|
V
|
K
|
A
|
L
|
D
|
F
|
R
|
T
|
180 |
TM4 | |||||||||
P
|
R
|
N
|
A
|
K
|
I
|
V
|
N
|
V
|
C
|
190 |
N
|
W
|
I
|
L
|
S
|
S
|
A
|
I
|
G
|
L
|
200 |
ECL2 | |||||||||
P
|
V
|
M
|
F
|
M
|
A
|
T
|
T
|
K
|
Y
|
210 |
R
|
Q
|
G
|
S
|
I
|
D
|
C
|
T
|
L
|
T
|
220 |
TM5 | |||||||||
F
|
S
|
H
|
P
|
T
|
W
|
Y
|
W
|
E
|
N
|
230 |
L
|
L
|
K
|
I
|
C
|
V
|
F
|
I
|
F
|
A
|
240 |
F
|
I
|
M
|
P
|
V
|
L
|
I
|
I
|
T
|
V
|
250 |
C
|
Y
|
G
|
L
|
M
|
I
|
L
|
R
|
L
|
K
|
260 |
ICL3 | TM6 | ||||||||
S
|
V
|
R
|
M
|
L
|
S
|
G
|
S
|
K
|
E
|
270 |
K
|
D
|
R
|
N
|
L
|
R
|
R
|
I
|
T
|
R
|
280 |
M
|
V
|
L
|
V
|
V
|
V
|
A
|
V
|
F
|
I
|
290 |
V
|
C
|
W
|
T
|
P
|
I
|
H
|
I
|
Y
|
V
|
300 |
ECL3 | |||||||||
I
|
I
|
K
|
A
|
L
|
I
|
T
|
I
|
P
|
E
|
310 |
TM7 | |||||||||
T
|
T
|
F
|
Q
|
T
|
V
|
S
|
W
|
H
|
F
|
320 |
C
|
I
|
A
|
L
|
G
|
Y
|
T
|
N
|
S
|
C
|
330 |
L
|
N
|
P
|
V
|
L
|
Y
|
A
|
F
|
L
|
D
|
340 |
H8 | |||||||||
E
|
N
|
F
|
K
|
R
|
C
|
F
|
R
|
E
|
F
|
350 |
C-term | |||||||||
C
|
I
|
P
|
T
|
S
|
S
|
T
|
I
|
E
|
Q
|
360 |
Q
|
N
|
S
|
A
|
R
|
I
|
R
|
Q
|
N
|
T
|
370 |
R
|
E
|
H
|
P
|
S
|
T
|
A
|
N
|
T
|
V
|
380 |
D
|
R
|
T
|
N
|
H
|
Q
|
L
|
E
|
N
|
L
|
390 |
E
|
A
|
E
|
T
|
A
|
P
|
L
|
P
|
|
|||||||||
N-term | |||||||||
|
G
|
P
|
G
|
N
|
I
|
S
|
D
|
C
|
S
|
14 |
D
|
P
|
L
|
A
|
P
|
A
|
S
|
C
|
S
|
P
|
24 |
A
|
P
|
G
|
S
|
W
|
L
|
N
|
L
|
S
|
H
|
34 |
V
|
D
|
G
|
N
|
Q
|
S
|
D
|
P
|
C
|
G
|
44 |
P
|
N
|
R
|
T
|
G
|
L
|
G
|
G
|
S
|
H
|
54 |
S
|
L
|
C
|
P
|
Q
|
T
|
G
|
S
|
P
|
S
|
64 |
TM1 | |||||||||
M
|
V
|
T
|
A
|
I
|
T
|
I
|
M
|
A
|
L
|
74 |
Y
|
S
|
I
|
V
|
C
|
V
|
V
|
G
|
L
|
F
|
84 |
G
|
N
|
F
|
L
|
V
|
M
|
Y
|
V
|
I
|
V
|
94 |
ICL1 | TM2 | ||||||||
R
|
Y
|
T
|
K
|
M
|
K
|
T
|
A
|
T
|
N
|
104 |
I
|
Y
|
I
|
F
|
N
|
L
|
A
|
L
|
A
|
D
|
114 |
A
|
L
|
A
|
T
|
S
|
T
|
L
|
P
|
F
|
Q
|
124 |
S
|
V
|
N
|
Y
|
L
|
M
|
G
|
T
|
W
|
P
|
134 |
ECL1 | TM3 | ||||||||
F
|
G
|
N
|
I
|
L
|
C
|
K
|
I
|
V
|
I
|
144 |
S
|
I
|
D
|
Y
|
Y
|
N
|
M
|
F
|
T
|
S
|
154 |
I
|
F
|
T
|
L
|
C
|
T
|
M
|
S
|
V
|
D
|
164 |
R
|
Y
|
I
|
A
|
V
|
C
|
H
|
P
|
V
|
K
|
174 |
ICL2 | TM4 | ||||||||
A
|
L
|
D
|
F
|
R
|
T
|
P
|
R
|
N
|
A
|
184 |
K
|
I
|
V
|
N
|
V
|
C
|
N
|
W
|
I
|
L
|
194 |
S
|
S
|
A
|
I
|
G
|
L
|
P
|
V
|
M
|
F
|
204 |
ECL2 | |||||||||
M
|
A
|
T
|
T
|
K
|
Y
|
R
|
Q
|
G
|
S
|
214 |
I
|
D
|
C
|
T
|
L
|
T
|
F
|
S
|
H
|
P
|
224 |
TM5 | |||||||||
T
|
W
|
Y
|
W
|
E
|
N
|
L
|
L
|
K
|
I
|
234 |
C
|
V
|
F
|
I
|
F
|
A
|
F
|
I
|
M
|
P
|
244 |
V
|
L
|
I
|
I
|
T
|
V
|
C
|
Y
|
G
|
L
|
254 |
M
|
I
|
L
|
R
|
L
|
K
|
S
|
V
|
R
|
M
|
264 |
ICL3 | TM6 | ||||||||
L
|
S
|
G
|
S
|
K
|
E
|
K
|
D
|
R
|
N
|
274 |
L
|
R
|
R
|
I
|
T
|
R
|
M
|
V
|
L
|
V
|
284 |
V
|
V
|
A
|
V
|
F
|
I
|
V
|
C
|
W
|
T
|
294 |
P
|
I
|
H
|
I
|
Y
|
V
|
I
|
I
|
K
|
A
|
304 |
ECL3 | TM7 | ||||||||
L
|
I
|
T
|
I
|
P
|
E
|
T
|
T
|
F
|
Q
|
314 |
T
|
V
|
S
|
W
|
H
|
F
|
C
|
I
|
A
|
L
|
324 |
G
|
Y
|
T
|
N
|
S
|
C
|
L
|
N
|
P
|
V
|
334 |
H8 | |||||||||
L
|
Y
|
A
|
F
|
L
|
D
|
E
|
N
|
F
|
K
|
344 |
R
|
C
|
F
|
R
|
E
|
F
|
C
|
I
|
P
|
T
|
354 |
C-term | |||||||||
S
|
S
|
T
|
I
|
E
|
Q
|
Q
|
N
|
S
|
A
|
364 |
R
|
I
|
R
|
Q
|
N
|
T
|
R
|
E
|
H
|
P
|
374 |
S
|
T
|
A
|
N
|
T
|
V
|
D
|
R
|
T
|
N
|
384 |
H
|
Q
|
L
|
E
|
N
|
L
|
E
|
A
|
E
|
T
|
394 |
A
|
P
|
L
|
P
|
398 |
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|