vipr1_human
NAME
8E3Y
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
vipr1_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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R
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P
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P
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S
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P
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L
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P
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A
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R
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10 |
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W
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L
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C
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V
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L
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A
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G
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A
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A
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20 |
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W
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A
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L
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G
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P
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A
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G
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G
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Q
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A
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30 |
A
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R
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L
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Q
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E
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E
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C
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D
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Y
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V
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40 |
Q
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M
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I
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E
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V
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Q
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H
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K
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Q
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C
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50 |
L
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E
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E
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A
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Q
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L
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E
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N
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E
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T
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60 |
I
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G
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C
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S
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K
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M
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W
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D
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N
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L
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70 |
T
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C
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W
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P
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A
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T
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P
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R
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G
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Q
|
80 |
V
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V
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V
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L
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P
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L
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I
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F
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90 |
K
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S
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Q
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G
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R
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N
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100 |
V
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S
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R
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S
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C
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T
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D
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E
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G
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W
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110 |
T
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H
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L
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E
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P
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G
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P
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Y
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P
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I
|
120 |
A
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C
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G
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L
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D
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D
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K
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A
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A
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S
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130 |
TM1 | |||||||||
L
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D
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E
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Q
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Q
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T
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M
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F
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Y
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G
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140 |
S
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V
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K
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T
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G
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Y
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T
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I
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G
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Y
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150 |
G
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L
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S
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L
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A
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T
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L
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L
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V
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A
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160 |
T
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A
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I
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L
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S
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L
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F
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R
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K
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L
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170 |
ICL1 | TM2 | ||||||||
H
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C
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T
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R
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N
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Y
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I
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H
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M
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H
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180 |
L
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F
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I
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S
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F
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I
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L
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R
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A
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A
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190 |
A
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V
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F
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I
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K
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D
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L
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A
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L
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F
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200 |
ECL1 | |||||||||
D
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S
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G
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E
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S
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D
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Q
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C
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S
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E
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210 |
TM3 | |||||||||
G
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S
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V
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G
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C
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K
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A
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A
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M
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V
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220 |
F
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F
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Q
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Y
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C
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V
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M
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A
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N
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F
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230 |
F
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W
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L
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L
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V
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E
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G
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L
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Y
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L
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240 |
ICL2 | |||||||||
Y
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T
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L
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L
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A
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V
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S
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F
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F
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S
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250 |
TM4 | |||||||||
E
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R
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K
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Y
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F
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W
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G
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Y
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I
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L
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260 |
I
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G
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W
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G
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V
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P
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S
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T
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F
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T
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270 |
M
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V
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W
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T
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I
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A
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R
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I
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H
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F
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280 |
ECL2 | |||||||||
E
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D
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Y
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G
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C
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W
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D
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T
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I
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N
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290 |
TM5 | |||||||||
S
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S
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L
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W
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W
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I
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I
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K
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G
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P
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300 |
I
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L
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T
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S
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V
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N
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F
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I
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310 |
L
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F
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I
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C
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I
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I
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R
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I
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L
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L
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320 |
ICL3 | |||||||||
Q
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K
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L
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R
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P
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P
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D
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I
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R
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K
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330 |
TM6 | |||||||||
S
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D
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S
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S
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P
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Y
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S
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R
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L
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A
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340 |
R
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S
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T
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L
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L
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L
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I
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P
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L
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F
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350 |
G
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V
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H
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Y
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I
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M
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F
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A
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F
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F
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360 |
ECL3 | TM7 | ||||||||
P
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D
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N
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F
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K
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P
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E
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V
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K
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M
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370 |
V
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F
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L
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V
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V
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G
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S
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F
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Q
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380 |
G
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F
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V
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V
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A
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I
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L
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Y
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C
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F
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390 |
H8 | |||||||||
L
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N
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G
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E
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V
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Q
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A
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E
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L
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R
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400 |
R
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K
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W
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R
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R
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W
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H
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L
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Q
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G
|
410 |
V
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L
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G
|
W
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N
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P
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K
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Y
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R
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H
|
420 |
C-term | |||||||||
P
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S
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G
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G
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S
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N
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G
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A
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T
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C
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430 |
S
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T
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Q
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V
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S
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M
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L
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T
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R
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V
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440 |
S
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P
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G
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A
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R
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R
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S
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S
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S
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F
|
450 |
Q
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A
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E
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V
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S
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L
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V
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|||||||||
N-term | |||||||||
|
G
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Q
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A
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A
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R
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L
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Q
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E
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E
|
36 |
C
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D
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Y
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V
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Q
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M
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I
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E
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V
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Q
|
46 |
H
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K
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Q
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C
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L
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E
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E
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A
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Q
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L
|
56 |
E
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N
|
E
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T
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I
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G
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C
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S
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K
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M
|
66 |
W
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D
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N
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L
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T
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C
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W
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P
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A
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T
|
76 |
P
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R
|
G
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Q
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V
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V
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V
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L
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A
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C
|
86 |
P
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L
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I
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F
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K
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L
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F
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S
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S
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I
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96 |
Q
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G
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R
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N
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V
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S
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R
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S
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C
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T
|
106 |
D
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E
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G
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W
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T
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H
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L
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E
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P
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G
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116 |
P
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Y
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P
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I
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A
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C
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G
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L
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D
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D
|
126 |
TM1 | |||||||||
K
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A
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A
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S
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L
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D
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E
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Q
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Q
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T
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136 |
M
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F
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Y
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G
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S
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V
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K
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T
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G
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Y
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146 |
T
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I
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G
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Y
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G
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L
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S
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L
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A
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T
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156 |
L
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L
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V
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A
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T
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A
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I
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L
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S
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L
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166 |
ICL1 | TM2 | ||||||||
F
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R
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K
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L
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H
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C
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T
|
R
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N
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Y
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176 |
I
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H
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M
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H
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L
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F
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I
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S
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F
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I
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186 |
L
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R
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A
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A
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A
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V
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F
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I
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K
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D
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196 |
ECL1 | |||||||||
L
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A
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L
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F
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D
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S
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G
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E
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S
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D
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206 |
TM3 | |||||||||
Q
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C
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S
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E
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G
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S
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V
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G
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C
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K
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216 |
A
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A
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M
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V
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F
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F
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Q
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Y
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C
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V
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226 |
M
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A
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N
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F
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F
|
W
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L
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L
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V
|
E
|
236 |
G
|
L
|
Y
|
L
|
Y
|
T
|
L
|
L
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A
|
V
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246 |
ICL2 | TM4 | ||||||||
S
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F
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F
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S
|
E
|
R
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K
|
Y
|
F
|
W
|
256 |
G
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Y
|
I
|
L
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I
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G
|
W
|
G
|
V
|
P
|
266 |
S
|
T
|
F
|
T
|
M
|
V
|
W
|
T
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I
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A
|
276 |
ECL2 | |||||||||
R
|
I
|
H
|
F
|
E
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D
|
Y
|
G
|
C
|
W
|
286 |
TM5 | |||||||||
D
|
T
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I
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N
|
S
|
S
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L
|
W
|
W
|
I
|
296 |
I
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K
|
G
|
P
|
I
|
L
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T
|
S
|
I
|
L
|
306 |
V
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N
|
F
|
I
|
L
|
F
|
I
|
C
|
I
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I
|
316 |
R
|
I
|
L
|
L
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Q
|
K
|
L
|
R
|
P
|
P
|
326 |
ICL3 | TM6 | ||||||||
D
|
I
|
R
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K
|
S
|
D
|
S
|
S
|
P
|
Y
|
336 |
S
|
R
|
L
|
A
|
R
|
S
|
T
|
L
|
L
|
L
|
346 |
I
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P
|
L
|
F
|
G
|
V
|
H
|
Y
|
I
|
M
|
356 |
ECL3 | |||||||||
F
|
A
|
F
|
F
|
P
|
D
|
N
|
F
|
K
|
P
|
366 |
TM7 | |||||||||
E
|
V
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K
|
M
|
V
|
F
|
E
|
L
|
V
|
V
|
376 |
G
|
S
|
F
|
Q
|
G
|
F
|
V
|
V
|
A
|
I
|
386 |
H8 | |||||||||
L
|
Y
|
C
|
F
|
L
|
N
|
G
|
E
|
V
|
Q
|
396 |
A
|
E
|
L
|
R
|
R
|
K
|
W
|
R
|
R
|
W
|
406 |
H
|
L
|
Q
|
G
|
V
|
L
|
G
|
W
|
N
|
P
|
416 |
C-term | |||||||||
K
|
Y
|
R
|
H
|
P
|
S
|
G
|
G
|
S
|
N
|
426 |
G
|
A
|
T
|
C
|
S
|
T
|
Q
|
V
|
S
|
M
|
436 |
L
|
T
|
R
|
V
|
S
|
P
|
G
|
A
|
R
|
R
|
446 |
S
|
S
|
S
|
F
|
Q
|
A
|
E
|
V
|
S
|
L
|
456 |
V
|
457 |
SCHEMATIC
Perspective:
Wild-type
Construct
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|