q76sf8_hhv8
NAME
8K4P
ORGANISM
HHV-8 (Human herpesvirus 8)
PROTEIN NAME
q76sf8_hhv8
SOURCE
TREMBL
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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A
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A
|
E
|
D
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F
|
L
|
T
|
I
|
F
|
10 |
|
|
|
|
|
|
|
|
|
|
L
|
D
|
D
|
D
|
E
|
S
|
W
|
N
|
E
|
T
|
20 |
|
|
|
|
|
|
|
|
|
|
L
|
N
|
M
|
S
|
G
|
Y
|
D
|
Y
|
S
|
G
|
30 |
|
|
|
|
|
|
|
|
|
|
N
|
F
|
S
|
L
|
E
|
V
|
S
|
V
|
C
|
E
|
40 |
|
|
|
|
|
|
||||
TM1 | |||||||||
M
|
T
|
T
|
V
|
V
|
P
|
Y
|
T
|
W
|
N
|
50 |
V
|
G
|
I
|
L
|
S
|
L
|
I
|
F
|
L
|
I
|
60 |
N
|
V
|
L
|
G
|
N
|
G
|
L
|
V
|
T
|
Y
|
70 |
I
|
F
|
C
|
K
|
H
|
R
|
S
|
R
|
A
|
G
|
80 |
TM2 | |||||||||
A
|
I
|
D
|
I
|
L
|
L
|
L
|
G
|
I
|
C
|
90 |
L
|
N
|
S
|
L
|
C
|
L
|
S
|
I
|
S
|
L
|
100 |
L
|
A
|
E
|
V
|
L
|
M
|
F
|
L
|
F
|
P
|
110 |
ECL1 | TM3 | ||||||||
N
|
I
|
I
|
S
|
T
|
G
|
L
|
C
|
R
|
L
|
120 |
E
|
I
|
F
|
F
|
Y
|
Y
|
L
|
Y
|
V
|
Y
|
130 |
L
|
D
|
I
|
F
|
S
|
V
|
V
|
C
|
V
|
S
|
140 |
L
|
V
|
R
|
Y
|
L
|
L
|
V
|
A
|
Y
|
S
|
150 |
ICL2 | TM4 | ||||||||
T
|
R
|
S
|
W
|
P
|
K
|
K
|
Q
|
S
|
L
|
160 |
G
|
W
|
V
|
L
|
T
|
S
|
A
|
A
|
L
|
L
|
170 |
I
|
A
|
L
|
V
|
L
|
S
|
G
|
D
|
A
|
C
|
180 |
ECL2 | |||||||||
R
|
H
|
R
|
S
|
R
|
V
|
V
|
D
|
P
|
V
|
190 |
S
|
K
|
Q
|
A
|
M
|
C
|
Y
|
E
|
N
|
A
|
200 |
TM5 | |||||||||
G
|
N
|
M
|
T
|
A
|
D
|
W
|
R
|
L
|
H
|
210 |
V
|
R
|
T
|
V
|
S
|
V
|
T
|
A
|
G
|
F
|
220 |
L
|
L
|
P
|
L
|
A
|
L
|
L
|
I
|
L
|
F
|
230 |
Y
|
A
|
L
|
T
|
W
|
C
|
V
|
V
|
R
|
R
|
240 |
ICL3 | TM6 | ||||||||
T
|
K
|
L
|
Q
|
A
|
R
|
R
|
K
|
V
|
R
|
250 |
G
|
V
|
I
|
V
|
A
|
V
|
V
|
L
|
L
|
F
|
260 |
F
|
V
|
F
|
C
|
F
|
P
|
Y
|
H
|
V
|
L
|
270 |
N
|
L
|
L
|
D
|
T
|
L
|
L
|
R
|
R
|
R
|
280 |
ECL3 | TM7 | ||||||||
W
|
I
|
R
|
D
|
S
|
C
|
Y
|
T
|
R
|
G
|
290 |
L
|
I
|
N
|
V
|
G
|
L
|
A
|
V
|
T
|
S
|
300 |
L
|
L
|
Q
|
A
|
L
|
Y
|
S
|
A
|
V
|
V
|
310 |
H8 | |||||||||
P
|
L
|
I
|
Y
|
S
|
C
|
L
|
G
|
S
|
L
|
320 |
F
|
R
|
Q
|
R
|
M
|
Y
|
G
|
L
|
F
|
Q
|
330 |
S
|
L
|
R
|
Q
|
S
|
F
|
M
|
S
|
G
|
A
|
340 |
|
|
||||
C-term | |||||
T
|
T
|
||||
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|||||||||
TM1 | |||||||||
|
Y
|
T
|
W
|
N
|
V
|
G
|
I
|
L
|
S
|
55 |
L
|
I
|
F
|
L
|
I
|
N
|
V
|
L
|
G
|
N
|
65 |
G
|
L
|
V
|
T
|
Y
|
I
|
F
|
C
|
K
|
H
|
75 |
TM2 | |||||||||
R
|
S
|
R
|
A
|
G
|
A
|
I
|
D
|
I
|
L
|
85 |
L
|
L
|
G
|
I
|
C
|
L
|
N
|
S
|
L
|
C
|
95 |
L
|
S
|
I
|
S
|
L
|
L
|
A
|
E
|
V
|
L
|
105 |
ECL1 | |||||||||
M
|
F
|
L
|
F
|
P
|
N
|
I
|
I
|
S
|
T
|
115 |
TM3 | |||||||||
G
|
L
|
C
|
R
|
L
|
E
|
I
|
F
|
F
|
Y
|
125 |
Y
|
L
|
Y
|
V
|
Y
|
L
|
D
|
I
|
F
|
S
|
135 |
V
|
V
|
C
|
V
|
S
|
L
|
V
|
R
|
Y
|
L
|
145 |
ICL2 | |||||||||
L
|
V
|
A
|
Y
|
S
|
T
|
R
|
S
|
W
|
P
|
155 |
TM4 | |||||||||
K
|
K
|
Q
|
S
|
L
|
G
|
W
|
V
|
L
|
T
|
165 |
S
|
A
|
A
|
L
|
L
|
I
|
A
|
L
|
V
|
L
|
175 |
ECL2 | |||||||||
S
|
G
|
D
|
A
|
C
|
R
|
H
|
R
|
S
|
R
|
185 |
V
|
V
|
D
|
P
|
V
|
S
|
K
|
Q
|
A
|
M
|
195 |
TM5 | |||||||||
C
|
Y
|
E
|
N
|
A
|
G
|
N
|
M
|
T
|
A
|
205 |
D
|
W
|
R
|
L
|
H
|
V
|
R
|
T
|
V
|
S
|
215 |
V
|
T
|
A
|
G
|
F
|
L
|
L
|
P
|
L
|
A
|
225 |
L
|
L
|
I
|
L
|
F
|
Y
|
A
|
L
|
T
|
W
|
235 |
ICL3 | |||||||||
C
|
V
|
V
|
R
|
R
|
T
|
K
|
L
|
Q
|
A
|
245 |
TM6 | |||||||||
R
|
R
|
K
|
V
|
R
|
G
|
V
|
I
|
V
|
A
|
255 |
V
|
V
|
L
|
L
|
F
|
F
|
V
|
F
|
C
|
F
|
265 |
P
|
Y
|
H
|
V
|
L
|
N
|
L
|
L
|
D
|
T
|
275 |
ECL3 | |||||||||
L
|
L
|
R
|
R
|
R
|
W
|
I
|
R
|
D
|
S
|
285 |
TM7 | |||||||||
C
|
Y
|
T
|
R
|
G
|
L
|
I
|
N
|
V
|
G
|
295 |
L
|
A
|
V
|
T
|
S
|
L
|
L
|
Q
|
A
|
L
|
305 |
Y
|
S
|
A
|
V
|
V
|
P
|
L
|
I
|
Y
|
S
|
315 |
H8 | |||||||||
C
|
L
|
G
|
S
|
L
|
F
|
R
|
Q
|
R
|
M
|
325 |
Y
|
G
|
L
|
F
|
Q
|
S
|
L
|
R
|
Q
|
S
|
335 |
|
|||||
F
|
M
|
S
|
G
|
A
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|