par1_human
NAME
8XOS
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
par1_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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G
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P
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R
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R
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L
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L
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L
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V
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A
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10 |
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|
|
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A
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C
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F
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S
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L
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C
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G
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P
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L
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L
|
20 |
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|
|
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S
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A
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R
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T
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R
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A
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R
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R
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P
|
E
|
30 |
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|
|
|
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S
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K
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A
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T
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N
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A
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T
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L
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D
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P
|
40 |
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|
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R
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S
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F
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L
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L
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R
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N
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P
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N
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D
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50 |
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|
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K
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Y
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E
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P
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F
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W
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E
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D
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E
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E
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60 |
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|
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|
|
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K
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N
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E
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S
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G
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L
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T
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E
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Y
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R
|
70 |
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|
|
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L
|
V
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S
|
I
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N
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K
|
S
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S
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P
|
L
|
80 |
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|
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|
|
|
|
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Q
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K
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Q
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L
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P
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A
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F
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I
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S
|
E
|
90 |
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|
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|
|
|
|
|
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D
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A
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S
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G
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Y
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L
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T
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S
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S
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W
|
100 |
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|
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|
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TM1 | |||||||||
L
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T
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L
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F
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V
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P
|
S
|
V
|
Y
|
T
|
110 |
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|
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|
|
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G
|
V
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F
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V
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V
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S
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L
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P
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L
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N
|
120 |
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|
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I
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M
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A
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I
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V
|
V
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F
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I
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L
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K
|
130 |
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ICL1 | TM2 | ||||||||
M
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K
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V
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K
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K
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P
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A
|
V
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V
|
Y
|
140 |
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|
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|
|
|
|
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M
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L
|
H
|
L
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A
|
T
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A
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D
|
V
|
L
|
150 |
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|
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F
|
V
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S
|
V
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L
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P
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F
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K
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I
|
S
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160 |
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ECL1 | |||||||||
Y
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Y
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F
|
S
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G
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S
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D
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W
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Q
|
F
|
170 |
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TM3 | |||||||||
G
|
S
|
E
|
L
|
C
|
R
|
F
|
V
|
T
|
A
|
180 |
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|
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A
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F
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Y
|
C
|
N
|
M
|
Y
|
A
|
S
|
I
|
190 |
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L
|
L
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M
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T
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V
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I
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S
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I
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D
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R
|
200 |
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ICL2 | |||||||||
F
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L
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A
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V
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V
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Y
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P
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M
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Q
|
S
|
210 |
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TM4 | |||||||||
L
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S
|
W
|
R
|
T
|
L
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G
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R
|
A
|
S
|
220 |
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|
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F
|
T
|
C
|
L
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A
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I
|
W
|
A
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L
|
A
|
230 |
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I
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A
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G
|
V
|
V
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P
|
L
|
L
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L
|
K
|
240 |
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ECL2 | |||||||||
E
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Q
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T
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I
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Q
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V
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P
|
G
|
L
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N
|
250 |
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|
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I
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T
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T
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C
|
H
|
D
|
V
|
L
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N
|
E
|
260 |
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TM5 | |||||||||
T
|
L
|
L
|
E
|
G
|
Y
|
Y
|
A
|
Y
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Y
|
270 |
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|
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F
|
S
|
A
|
F
|
S
|
A
|
V
|
F
|
F
|
F
|
280 |
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|
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|
|
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V
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P
|
L
|
I
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I
|
S
|
T
|
V
|
C
|
Y
|
290 |
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|
|
|
|
|
V
|
S
|
I
|
I
|
R
|
C
|
L
|
S
|
S
|
S
|
300 |
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|
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ICL3 | TM6 | ||||||||
A
|
V
|
A
|
N
|
R
|
S
|
K
|
K
|
S
|
R
|
310 |
|
|
|
|
|
|
|
|
|
|
A
|
L
|
F
|
L
|
S
|
A
|
A
|
V
|
F
|
C
|
320 |
|
|
|
|
|
|
|
|
|
|
I
|
F
|
I
|
I
|
C
|
F
|
G
|
P
|
T
|
N
|
330 |
|
|
|
|
|
|
|
|
|
|
V
|
L
|
L
|
I
|
A
|
H
|
Y
|
S
|
F
|
L
|
340 |
|
|
|
|
|
|
|
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|
|
ECL3 | TM7 | ||||||||
S
|
H
|
T
|
S
|
T
|
T
|
E
|
A
|
A
|
Y
|
350 |
|
|
|
|
|
|
|
|
|
|
F
|
A
|
Y
|
L
|
L
|
C
|
V
|
C
|
V
|
S
|
360 |
|
|
|
|
|
|
|
|
|
|
S
|
I
|
S
|
C
|
C
|
I
|
D
|
P
|
L
|
I
|
370 |
|
|
|
|
|
|
|
|
|
|
H8 | |||||||||
Y
|
Y
|
Y
|
A
|
S
|
S
|
E
|
C
|
Q
|
R
|
380 |
|
|
|
|
|
|
|
|
|
|
Y
|
V
|
Y
|
S
|
I
|
L
|
C
|
C
|
K
|
E
|
390 |
|
|
|
|
|
|
|
|
|
|
C-term | |||||||||
S
|
S
|
D
|
P
|
S
|
S
|
Y
|
N
|
S
|
S
|
400 |
|
|
|
|
|
|
|
|
|
|
G
|
Q
|
L
|
M
|
A
|
S
|
K
|
M
|
D
|
T
|
410 |
|
|
|
|
|
|
|
|
|
|
C
|
S
|
S
|
N
|
L
|
N
|
N
|
S
|
I
|
Y
|
420 |
|
|
|
|
|
K
|
K
|
L
|
L
|
T
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
|
|
|
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|