Structure information

AT2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6JOD

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

A

REFERENCE

10.1016/J.STR.2019.12.003

PUBLICATION DATE

Jan. 15, 2020

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
angiotensin II W100 2.60x60 TM2 hydrophobic
angiotensin II Y103 2.63x63 TM2 Van der Waals
angiotensin II Y103 2.63x63 TM2 polar (hydrogen bond)
angiotensin II Y104 2.64x64 TM2 polar (hydrogen bond)
angiotensin II Y108 ECL1 Van der Waals
angiotensin II Y108 ECL1 hydrophobic
angiotensin II L124 3.32x32 TM3 Van der Waals
angiotensin II L124 3.32x32 TM3 hydrophobic
angiotensin II T125 3.33x33 TM3 Van der Waals
angiotensin II M128 3.36x36 TM3 hydrophobic
angiotensin II M128 3.36x36 TM3 Van der Waals
angiotensin II R182 4.64x65 TM4 polar (charge-assisted hydrogen bond)
angiotensin II C195 45.50x50 ECL2 Van der Waals
angiotensin II I196 45.51x51 ECL2 Van der Waals
angiotensin II I196 45.51x51 ECL2 hydrophobic
angiotensin II M197 45.52x52 ECL2 polar (hydrogen bond with backbone)
angiotensin II M197 45.52x52 ECL2 Van der Waals
angiotensin II Y204 5.31x32 TM5 Van der Waals
angiotensin II Y204 5.31x32 TM5 polar (hydrogen bond)
angiotensin II K215 5.42x43 TM5 polar (charge-assisted hydrogen bond)
angiotensin II W269 6.48x48 TM6 Van der Waals
angiotensin II W269 6.48x48 TM6 hydrophobic
angiotensin II F272 6.51x51 TM6 hydrophobic
angiotensin II F272 6.51x51 TM6 Van der Waals
angiotensin II D279 6.58x58 TM6 polar (charge-assisted hydrogen bond)
angiotensin II W283 6.62x62 TM6 Van der Waals
angiotensin II W283 6.62x62 TM6 hydrophobic
angiotensin II I293 7.28x27 TM7 Van der Waals
angiotensin II D297 7.32x31 TM7 Van der Waals
angiotensin II L300 7.35x34 TM7 Van der Waals
angiotensin II L300 7.35x34 TM7 hydrophobic
angiotensin II P301 7.36x35 TM7 Van der Waals
angiotensin II I304 7.39x38 TM7 hydrophobic
angiotensin II I304 7.39x38 TM7 Van der Waals

Ligands

angiotensin II

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N V L F G I V F I I Y Y L I P I A D 1 F N L A V A D L L L L A T L P L W A T Y 2 C T I F F I S A F M N L T L F S G F V K 3 A S Y I V P L V W C M A C L S S L P T 4 Y C T A I F I L P I I F G L I N K M L A I 5 A A V V L A F I I C W L P F H V L T F L 6 F P N V C S N T F G L L I A F P L A L 7
Download: PNG | SVG
ICL1 K G P K K ICL1ECL1 Y D W L F ECL1ICL2 P F L S Q R R ICL2ECL2 D V R T I E Y L G V N A C I M A F P P E ECL2ICL3 N S Y ICL3ECL3 V I N ECL3N-term M K G N S T L A T T S K N I T S G L H F G L V N I S G N N E S T L N C S Q K P S D K H L N-termC-term I T W L Q G K R E S M S C R K S S S L R E M E T F V S C-term D A I P I L Y Y I I F V I G F L V N I V V V T L F C C Q V S S I Y I F N L A V A D L L L L A T L P L W A T Y Y S Y R G P V M C K V F G S F L T L N M F A S I F F I T C M S V D R Y Q S V I Y N P W Q A S Y I V P L V W C M A C L S S L P T F Y F R K Y A Q W S A G I A L M K N I L G F I I P L I F I A T C Y F G I R K H L L K T G K N R I T R D Q V L K M A A A V V L A F I I C W L P F H V L T F L D A L A W M G S C E V I A V I D L A L P F A I L L G F T N S C V N P F L Y C F V G N R L R S P F Q Q K V F R V
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
AT2 receptor
TM2
2x60 2.60x60 W100
2x63 2.63x63 Y103
2x64 2.64x64 Y104
TM3
3x32 3.32x32 L124
3x33 3.33x33 T125
3x36 3.36x36 M128
TM4
4x65 4.64x65 R182
ECL2
45x50 45.50x50 C195
45x51 45.51x51 I196
45x52 45.52x52 M197
TM5
5x32 5.31x32 Y204
5x43 5.42x43 K215
TM6
6x48 6.48x48 W269
6x51 6.51x51 F272
6x58 6.58x58 D279
6x62 6.62x62 W283
TM7
7x27 7.28x27 I293
7x31 7.32x31 D297
7x34 7.35x34 L300
7x35 7.36x35 P301
7x38 7.39x38 I304