Structure information

calcitonin receptor-like receptor

PROTEIN CLASS

Class B1 (Secretin)

PDB CODE

7KNU

SPECIES

Homo sapiens

RESOLUTION

3.490

PREFERRED CHAIN

R

REFERENCE

10.1126/SCIENCE.ABF7258

PUBLICATION DATE

Feb. 24, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Calcitonin gene-related peptide 1 W72 N-term aromatic (face-to-edge)
Calcitonin gene-related peptide 1 F92 N-term hydrophobic
Calcitonin gene-related peptide 1 D94 N-term polar (charge-assisted hydrogen bond)
Calcitonin gene-related peptide 1 F95 N-term Van der Waals
Calcitonin gene-related peptide 1 H114 N-term polar (hydrogen bond)
Calcitonin gene-related peptide 1 H114 N-term Van der Waals
Calcitonin gene-related peptide 1 S117 N-term polar (hydrogen bond)
Calcitonin gene-related peptide 1 S117 N-term Van der Waals
Calcitonin gene-related peptide 1 W121 N-term polar (hydrogen bond)
Calcitonin gene-related peptide 1 W121 N-term Van der Waals
Calcitonin gene-related peptide 1 T122 N-term polar (hydrogen bond with backbone)
Calcitonin gene-related peptide 1 T122 N-term Van der Waals
Calcitonin gene-related peptide 1 Y124 N-term Van der Waals
Calcitonin gene-related peptide 1 Y124 N-term hydrophobic
Calcitonin gene-related peptide 1 T125 N-term Van der Waals
Calcitonin gene-related peptide 1 N128 N-term Van der Waals
Calcitonin gene-related peptide 1 N128 N-term polar (hydrogen bond)

Ligands

Calcitonin gene-related peptide 1

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Residue Diagrams

L L S A I S L G H G I I T L Y F L N L A 1 K N L F F S F V C N S V V T I I H L T A 2 C L M W F Y N C G M L Y L H I F Q S V K 3 H L M W Y Y F G L W G F P L I P A C I H A 4 L F F L N V L L A A C I P G H I I Y L L H 5 L I L V P L L G I E F V L I P W 6 T S V L L G Q F H M L I H M I Y D Y V 7
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ICL1 K S L S ICL1ECL1 A N N Q A L V A T N P ECL1ICL2 A V F A E K Q ICL2ECL2 N D N C W I S S D ECL2ICL3 V T H Q A E S N L ICL3ECL3 R P E G ECL3N-term M E K K C T L Y F L V L L P F F M I L V T A E L E E S P E D S I Q L G V T R N K I M T A Q Y E C Y Q K I M Q D P I Q Q A E G V Y C N R T W D G W L C W N D V A A G T E S M Q L C P D Y F Q D F D P S E K V T K I C D Q D G N W F R H P A S N R T W T N Y T Q C N V N-termC-term E A L R S A S Y T V S T I S D G P G Y S H D C P S E H L N G K S I H D I E N V L L K P E N L Y N C-term N T H E K V K T A L N L F Y L T I I G H G L S I A S L L I S L G I F F Y F C Q R I T L H K N L F F S F V C N S V V T I I H L T A V V S C K V S Q F I H L Y L M G C N Y F W M L C E G I Y L H T L I V V H L M W Y Y F L G W G F P L I P A C I H A I A R S L Y Y T H L L Y I I H G P I C A A L L V N L F F L L N I V R V L I T K L K Y M K A V R A T L I L V P L L G I E F V L I P W K I A E E V Y D Y I M H I L M H F Q G L L V S T I F C F F N G E L R R Y K I S F S V Q A I N W N Q Q F G N N S
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Residue Table


GPCRdb(A)
GPCRdb(B)
calcitonin receptor-like receptor