Structure information

Rhodopsin

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7MTA

SPECIES

Bos taurus

RESOLUTION

4.100

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-021-03721-X

PUBLICATION DATE

July 7, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Retinal (all-trans) I189 45.52x52 ECL2 hydrophobic
Retinal (all-trans) Y191 ECL2 hydrophobic
Retinal (all-trans) M207 5.42x43 TM5 hydrophobic
Retinal (all-trans) F208 5.43x44 TM5 hydrophobic
Retinal (all-trans) F212 5.47x47 TM5 hydrophobic
Retinal (all-trans) W265 6.48x48 TM6 hydrophobic
Retinal (all-trans) Y268 6.51x51 TM6 hydrophobic
Retinal (all-trans) A269 6.52x52 TM6 hydrophobic
Retinal (all-trans) A272 6.55x55 TM6 hydrophobic
Retinal (all-trans) A292 7.39x38 TM7 hydrophobic

Ligands

Retinal (all-trans)

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Residue Diagrams

F N I P F G L M I L L F M Y A A L M S F 1 L N L A V A D L F M V G F G F T T T L Y T 2 V V L S W L A I E G G L T A F F G E L N 3 A I M G V A F T W V M A L A C A A P P L 4 Y C F F I V I L P I I F H V V F M Y I V F 5 I I M V I A F L I C W L P Y A G V A F Y 6 V P N Y V A S T K A F F A P I T M F I 7
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ICL1 K K L R ICL1ECL1 Y F V F ECL1ICL2 P M S N F R F ICL2ECL2 W S R Y I P E G M Q C S C G I D Y Y T P H E E T ECL2ICL3 Q E ICL3ECL3 Q G S D F ECL3N-term M N G T E G P N F Y V P F S N K T G V V R S P F E A P Q Y Y L A N-termC-term C G K N P L G D D E A S T T V S K T E T S Q V A P A C-term E P W Q F S M L A A Y M F L L I M L G F P I N F L T L Y V T V Q H T P L N Y I L L N L A V A D L F M V F G G F T T T L Y T S L H G G P T G C N L E G F F A T L G G E I A L W S L V V L A I E R Y V V V C K G E N H A I M G V A F T W V M A L A C A A P P L V G N N E S F V I Y M F V V H F I I P L I V I F F C Y G Q L V F T V K E A A A Q Q S A T T Q K A E K E V T R M V I I M V I A F L I C W L P Y A G V A F Y I F T H G P I F M T I P A F F A K T S A V Y N P V I Y I M M N K Q M V T F R N C T L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
Rhodopsin
ECL2
45x52 45.52x52 I189
TM5
5x43 5.42x43 M207
5x44 5.43x44 F208
5x47 5.47x47 F212
TM6
6x48 6.48x48 W265
6x51 6.51x51 Y268
6x52 6.52x52 A269
6x55 6.55x55 A272
TM7
7x38 7.39x38 A292