Structure information

FPR2/ALX

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7T6V

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-022-28586-0

PUBLICATION DATE

March 30, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
synthetic peptide V105 3.32x32 TM3 hydrophobic
synthetic peptide D106 3.33x33 TM3 polar (charge-assisted hydrogen bond)
synthetic peptide L109 3.36x36 TM3 Van der Waals
synthetic peptide L109 3.36x36 TM3 hydrophobic
synthetic peptide F110 3.37x37 TM3 Van der Waals
synthetic peptide F110 3.37x37 TM3 hydrophobic
synthetic peptide C176 45.50x50 ECL2 Van der Waals
synthetic peptide F178 45.52x52 ECL2 hydrophobic
synthetic peptide F178 45.52x52 ECL2 Van der Waals
synthetic peptide R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
synthetic peptide R205 5.42x43 TM5 polar (charge-assisted hydrogen bond)
synthetic peptide W254 6.48x48 TM6 Van der Waals
synthetic peptide F257 6.51x51 TM6 Van der Waals
synthetic peptide V284 7.35x34 TM7 Van der Waals
synthetic peptide V284 7.35x34 TM7 hydrophobic

Ligands

synthetic peptide

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Residue Diagrams

G N G L V G L V F T V G L V V L P L I R 1 L N L A L A D F S F T A T L P F L I V S 2 F G I L F V S G F L N I D V V I H I L K 3 A M K V I V G P W I L A L V L T L P V 4 Y C I A V I S M P L S F G I V F R I I G R 5 T A V V A S F F I C W F P F Q L V A L L 6 M P N L C S N F F A L S S T P N V L I 7
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ICL1 T R ICL1ECL1 E K W P F ECL1ICL2 P V W A Q N H R ICL2ECL2 T T V T I P N G D T Y C T F N F A S W G G ECL2ICL3 M I K S ICL3ECL3 L K E M L F Y G K ECL3N-term M E T N F S T P L N E Y E E V S Y E N-termC-term P T S L E R A L S E D S A P T N D T A A N S A S P P A E T E L Q A M C-term S A G Y T V L R I L P L V V L G V T F V L G V L G N G L V I W V A G F R M T V T T I C Y L N L A L A D F S F T A T L P F L I V S M A M G G W F L C K L I H I V V D I N L F G S V F L I G F I A L D R C I C V L H T V S L A M K V I V G P W I L A L V L T L P V F L F L T P E E R L K V A I T M L T A R G I I R F V I G F S L P M S I V A I C Y G L I A A K I H K K G S R P L R V L T A V V A S F F I C W F P F Q L V A L L G T V W Y K I I D I L V N P T S S L A F F N S C L N P M L Y V F V G Q D L I H F R E R S L
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Residue Table


GPCRdb(A)
GPCRdb(A)
FPR2/ALX
TM3
3x32 3.32x32 V105
3x33 3.33x33 D106
3x36 3.36x36 L109
3x37 3.37x37 F110
ECL2
45x50 45.50x50 C176
45x52 45.52x52 F178
TM5
5x39 5.38x39 R201
5x43 5.42x43 R205
TM6
6x48 6.48x48 W254
6x51 6.51x51 F257
TM7
7x34 7.35x34 V284