Structure information

κ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8DZR

SPECIES

Homo sapiens

RESOLUTION

2.610

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-023-06030-7

PUBLICATION DATE

May 3, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL277863 L135 3.29x29 TM3 hydrophobic
CHEMBL277863 Y139 3.33x33 TM3 hydrophobic
CHEMBL277863 M142 3.36x36 TM3 hydrophobic
CHEMBL277863 V230 5.42x43 TM5 hydrophobic
CHEMBL277863 W287 6.48x48 TM6 hydrophobic
CHEMBL277863 I290 6.51x51 TM6 hydrophobic
CHEMBL277863 I294 6.55x55 TM6 hydrophobic
CHEMBL277863 I316 7.39x38 TM7 hydrophobic
CHEMBL277863 Y320 7.43x42 TM7 hydrophobic

Ligands

CHEMBL277863

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Residue Diagrams

S N G V L G V V F V V S Y V A T I I V P 1 F N L A L A D A L V T T T M P F Q S T V 2 M T L T F I S T F M N Y Y D I S I V I K 3 A K I I N I C I W L L S S S V G I S A I 4 Y C V I I I L V P I V F A F I F V C I K M 5 L V V V A V F V V C W T P I H I F I L V 6 I P N L S S N T Y G L A I C F Y Y S S 7
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ICL1 T K M K ICL1ECL1 S W P F ECL1ICL2 P V K A L D F R ICL2ECL2 G T K V R E D V D V I E C S L Q F P D D ECL2ICL3 R L L S G ICL3ECL3 S T S H ECL3N-term M D S P I Q I F R G E P G P T C A P S A C L P P N S S A W F P G W A E P D S N G S A G S E D A Q L E P A H I S P N-termC-term P L K M R M E R Q S T S R V R N T V Q D P A Y L R D I D G M N K P V C-term A I P V I I T A V Y S V V F V V G L V G N S L V M F V I I R Y T A T N I Y I F N L A L A D A L V T T T M P F Q S T V Y L M N G D V L C K I V I S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P L K A K I I N I C I W L L S S S V G I S A I V L G D Y S W W D L F M K I C V F I F A F V I P V L I I I V C Y T L M I L R L K S V S R E K D R N L R R I T R L V L V V V A V F V V C W T P I H I F I L V E A L G S T A A L S S Y Y F C I A L G Y T N S S L N P I L Y A F L D E N F R D F K R C F C F
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Residue Table


GPCRdb(A)
GPCRdb(A)
κ receptor
TM3
3x29 3.29x29 I135
3x33 3.33x33 Y139
3x36 3.36x36 M142
TM5
5x43 5.42x43 V230
TM6
6x48 6.48x48 W287
6x51 6.51x51 I290
6x55 6.55x55 I294
TM7
7x38 7.39x38 I316
7x42 7.43x42 Y320