Structure information

M3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8E9Z

SPECIES

Homo sapiens

RESOLUTION

2.690

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-022-05489-0

PUBLICATION DATE

Nov. 30, 2022
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
iperoxo Y149 3.33x33 TM3 hydrophobic
iperoxo V156 3.40x40 TM3 hydrophobic
iperoxo A239 5.46x461 TM5 Van der Waals
iperoxo A239 5.46x461 TM5 polar (hydrogen bond with backbone)
iperoxo F240 5.47x47 TM5 Van der Waals
iperoxo F240 5.47x47 TM5 polar (hydrogen bond with backbone)
iperoxo W504 6.48x48 TM6 hydrophobic
iperoxo W504 6.48x48 TM6 Van der Waals
iperoxo Y507 6.51x51 TM6 hydrophobic
iperoxo Y507 6.51x51 TM6 Van der Waals
iperoxo N508 6.52x52 TM6 polar (hydrogen bond)
iperoxo Y530 7.39x38 TM7 hydrophobic
iperoxo Y530 7.39x38 TM7 Van der Waals
iperoxo C533 7.42x41 TM7 hydrophobic
iperoxo C533 7.42x41 TM7 Van der Waals
iperoxo Y534 7.43x42 TM7 hydrophobic
iperoxo Y534 7.43x42 TM7 Van der Waals
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 17 of 17 entries

Ligands

iperoxo

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Residue Diagrams

I N G I I T V L A L I G T L F A I F V V 1 L S L A C A D L I I G I V S M N L F T T Y 2 V L L N M V S A N S A V Y D I A L W L D 3 A G V M I G L A W V I S F V L W A P A I 4 Y L I T M I T V P M Y F A A I A T G F T I 5 S A I L L A F I I T W T P Y N I M V L V 6 V P N V T S N I Y C L W Y G L N W F T 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term T V W Q V V F I A F L T G I L A L V T I I G N I L V I V S F K V N T V N N Y F L L S L A C A D L I I G V I S M N L F T T Y I I M G N L A C D L W L A I D Y V A S N A S V M N L L V I S F D R Y F S I T R T T K R A G V M I G L A W V I S F V L W A P A I L F W Q Y F V G E P T I T F G T A I A A F Y M P V T I M T I L Y W R I Y K E T E K R T K E L A G L R M S L V K E K K A A Q T L S A I L L A F I I T W T P Y N I M V L V N T F C P K T F W N L G Y W L C Y I N S T V N P V C Y A L C N K T F K M F R T T L L L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
M3 receptor
TM3
3x33 3.33x33 Y149
3x40 3.40x40 V156
TM5
5x461 5.46x461 A239
5x47 5.47x47 F240
TM6
6x48 6.48x48 W504
6x51 6.51x51 Y507
6x52 6.52x52 N508
TM7
7x38 7.39x38 Y530
7x41 7.42x41 C533
7x42 7.43x42 Y534