Structure information

μ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8EFB

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELL.2022.09.041

PUBLICATION DATE

Nov. 9, 2022
|

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
OLICERIDINE Q126 2.60x60 TM2 polar (hydrogen bond)
OLICERIDINE N129 2.63x63 TM2 Van der Waals
OLICERIDINE I146 3.29x29 TM3 hydrophobic
OLICERIDINE I146 3.29x29 TM3 Van der Waals
OLICERIDINE D149 3.32x32 TM3 polar (charge-assisted hydrogen bond)
OLICERIDINE Y150 3.33x33 TM3 hydrophobic
OLICERIDINE Y150 3.33x33 TM3 Van der Waals
OLICERIDINE M153 3.36x36 TM3 polar (hydrogen bond)
OLICERIDINE C219 45.50x50 ECL2 Van der Waals
OLICERIDINE C219 45.50x50 ECL2 hydrophobic
OLICERIDINE W295 6.48x48 TM6 Van der Waals
OLICERIDINE W295 6.48x48 TM6 aromatic (edge-to-face)
OLICERIDINE I298 6.51x51 TM6 hydrophobic
OLICERIDINE I298 6.51x51 TM6 Van der Waals
OLICERIDINE H299 6.52x52 TM6 Van der Waals
OLICERIDINE I324 7.39x38 TM7 hydrophobic
OLICERIDINE I324 7.39x38 TM7 Van der Waals
OLICERIDINE G327 7.42x41 TM7 Van der Waals
OLICERIDINE Y328 7.43x42 TM7 Van der Waals
OLICERIDINE Y328 7.43x42 TM7 hydrophobic
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 20 of 20 entries

Ligands

OLICERIDINE

3D interaction viewer Download PDB file
  |  

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I I N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7
Download: PNG | SVG
ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I I N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
μ receptor
TM2
2x60 2.60x60 Q126
2x63 2.63x63 N129
TM3
3x29 3.29x29 I146
3x32 3.32x32 D149
3x33 3.33x33 Y150
3x36 3.36x36 M153
ECL2
45x50 45.50x50 C219
TM6
6x48 6.48x48 W295
6x51 6.51x51 I298
6x52 6.52x52 H299
TM7
7x38 7.39x38 I324
7x41 7.42x41 G327
7x42 7.43x42 Y328