Structure information

FFA1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8EJK

SPECIES

Homo sapiens

RESOLUTION

3.400

PREFERRED CHAIN

R

REFERENCE

10.1073/PNAS.2219569120

PUBLICATION DATE

May 24, 2023

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
fasiglifam A83 3.29x29 TM3 hydrophobic
fasiglifam V84 3.30x30 TM3 hydrophobic
fasiglifam F87 3.33x33 TM3 hydrophobic
fasiglifam L138 4.57x57 TM4 hydrophobic
fasiglifam F142 4.61x61 TM4 hydrophobic
fasiglifam L158 ECL2 hydrophobic
fasiglifam L171 45.51x51 ECL2 hydrophobic
fasiglifam R183 5.39x40 TM5 polar (charge-assisted hydrogen bond)
fasiglifam L186 5.42x43 TM5 Van der Waals
fasiglifam Y240 6.51x51 TM6 Van der Waals

Ligands

fasiglifam

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

V N L P F G L A F A A V Y L G F S L Q P 1 L N L G C S D L L L T V S L P L K A V E 2 A A L F G G G A Y L P F F H A V A F V P 3 S W G V C A A I W A L V L C H L G L V F 4 Y C F A T I A L P L F F L L L S L S F R A 5 A G G A L L T L L L C V G P Y N A S N V A 6 L P N L V V S W A G T I L G L K R W S 7
Download: PNG | SVG
ICL1 L ICL1ECL1 G A W P L ECL1ICL2 P L G Y Q A F R ICL2ECL2 P G G W L D H S N T S L G I N T P V N G S P V C L E A W ECL2ICL3 S G L T H ICL3ECL3 P N L G ECL3N-term M D L N-termC-term G G K S Q K C-term P P Q L S F G L Y V A A F A L G F P L N V L A I R G A T A H A R L R T P S L V Y A L N L G C S D L L L T V S L P L K A V E A L A S P A S L C P V F A V A H F F P L Y A G G G F L A A L S A G R Y L G A A F R P C Y S W G V C A A I W A L V L C H L G L V F G L E A D P A S A G P A R F S L S L L L F F L P L A I T A F C Y V G C L R A L A R R R K L R A A W V A G G A L L T L L L C V G P Y N A S N V A S F L Y G S W R K L G L I T G A W S V V L N P L V T G Y L G R G T V C Q P G L K A A R T
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
FFA1 receptor
TM3
3x29 3.29x29 A83
3x30 3.30x30 V84
3x33 3.33x33 F87
TM4
4x57 4.57x57 L138
4x61 4.61x61 F142
ECL2
45x51 45.51x51 L171
TM5
5x40 5.39x40 R183
5x43 5.42x43 L186
TM6
6x51 6.51x51 Y240