Structure information

FFA2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8J22

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

C

REFERENCE

10.1038/S41422-023-00914-Z

PUBLICATION DATE

Jan. 24, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL4176503 F87 3.30x30 TM3 hydrophobic
CHEMBL4176503 Y90 3.33x33 TM3 hydrophobic
CHEMBL4176503 V144 4.60x60 TM4 hydrophobic
CHEMBL4176503 I145 4.61x61 TM4 hydrophobic
CHEMBL4176503 V147 4.63x63 TM4 hydrophobic
CHEMBL4176503 F168 ECL2 hydrophobic
CHEMBL4176503 V175 5.34x35 TM5 hydrophobic
CHEMBL4176503 V176 5.35x36 TM5 hydrophobic
CHEMBL4176503 V179 5.38x39 TM5 hydrophobic
CHEMBL4176503 R180 5.39x40 TM5 polar (charge-assisted hydrogen bond)
CHEMBL4176503 L183 5.42x43 TM5 Van der Waals
CHEMBL4176503 Y238 6.51x51 TM6 Van der Waals
CHEMBL4176503 R255 7.35x34 TM7 polar (charge-assisted hydrogen bond)

Ligands

CHEMBL4176503

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

L N A P L G T L F I I I Y A M L I L S S 1 L S L T L A D L L L L L L L P F K I I E 2 G A L L W T S C Y I S S Y F G F S T L A 3 G V I A A L V A W V M S F G H C T I V I 4 Y C F I T V A M P I F F L V L C L E L R V 5 A V V T L L N F V L C F G P Y N V S H L V 6 L P D L S A N L S S F V V A I S R W 7
Download: PNG | SVG
ICL1 P Q P ICL1ECL1 N F R W Y L ECL1ICL2 P V Q Y K L S R ICL2ECL2 T E Q V R S G N E I T C Y E N F T D N ECL2ICL3 P L V ICL3ECL3 K S P W ECL3N-term M L N-termC-term R N Q G S S L L G R R G K D T A E G T N E D R G V G Q G E G M P S S D F T T E C-term P D W K S S L I L M A Y I I I F L T G L P A N L L A L R A F V G R I R Q A P V H I L L L S L T L A D L L L L L L L P F K I I E A A S P K V V C A L T S F G F Y S S I Y C S T W L L A G I S I E R Y L G V A F R P L Y G V I A A L V A W V M S F G H C T I V I I V Q Y L N T Q L D V V L P V R L E L C L V L F F I P M A V T I F C Y W R F V W I M L S Q G A Q R R R R A V G L A V V T L L N F L V C F G P Y N V S H L V G Y H Q R W R S I A V V F S S L N A S L D P L L F Y F S S S V F G R L V R R A G L Q V
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
FFA2 receptor
TM3
3x30 3.30x30 F87
3x33 3.33x33 Y90
TM4
4x60 4.60x60 V144
4x61 4.61x61 I145
4x63 4.63x63 V147
TM5
5x35 5.34x35 V175
5x36 5.35x36 V176
5x39 5.38x39 V179
5x40 5.39x40 R180
5x43 5.42x43 L183
TM6
6x51 6.51x51 Y238
TM7
7x34 7.35x34 R255