Structure information

HCA2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8J6L

SPECIES

Homo sapiens

RESOLUTION

3.050

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELREP.2023.113406

PUBLICATION DATE

April 3, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
nicotinic acid L83 2.60x60 TM2 hydrophobic
nicotinic acid F180 ECL2 hydrophobic
nicotinic acid F277 7.36x35 TM7 aromatic (edge-to-face)
nicotinic acid L280 7.39x38 TM7 hydrophobic
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 4 of 4 entries

Ligands

nicotinic acid

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Residue Diagrams

G N G L L G F I F E L G L V P P L V K V 1 F N L A V A D F L L I I C L P F L M D N 2 V T L F I I S G Q R N M A L M F L M L R 3 A A I I S C L L W G I T I G L T V H L L 4 S C F L I I G L P L F F E L L F M A E H W 5 M V V A I V F V I C F L P S V V V R I R 6 V P D L M S N M Y T F S L T I F F A L 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term F I V K V L P P V L G L E F I F G L L G N G L A L W I F C F H K S S R I F L F N L A V A D F L L I I C L P F L M D N Y V R R G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H S N R T A A I I S C L L W G I T I G L T V H L L K K K Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F S T C L F P N F L I N R
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Residue Table


GPCRdb(A)
GPCRdb(A)
HCA2 receptor
TM2
2x60 2.60x60 L83
TM7
7x35 7.36x35 F277
7x38 7.39x38 L280