Structure information

mGlu2 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

8JD4

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

2

REFERENCE

10.1038/S41422-023-00830-2

PUBLICATION DATE

June 21, 2023
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
L-glutamic acid R57 N-term polar (charge-assisted hydrogen bond)
L-glutamic acid S143 N-term polar (hydrogen bond)
L-glutamic acid S143 N-term Van der Waals
L-glutamic acid Y144 N-term Van der Waals
L-glutamic acid S145 N-term Van der Waals
L-glutamic acid S145 N-term polar (hydrogen bond with backbone)
L-glutamic acid S145 N-term polar (hydrogen bond)
L-glutamic acid A166 N-term Van der Waals
L-glutamic acid A166 N-term polar (hydrogen bond with backbone)
L-glutamic acid S167 N-term Van der Waals
L-glutamic acid T168 N-term polar (hydrogen bond with backbone)
L-glutamic acid T168 N-term polar (hydrogen bond)
L-glutamic acid Y216 N-term hydrophobic
L-glutamic acid Y216 N-term Van der Waals
L-glutamic acid D295 N-term polar (charge-assisted hydrogen bond)
L-glutamic acid K377 N-term polar (charge-assisted hydrogen bond)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 16 of 16 entries

Ligands

L-glutamic acid

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Residue Diagrams

L T A L A G L C A I T V P G V A W A D G 1 Y I L L G G V F L C Y C M T F I F I A 2 T L L A S Y C V S F A T G L G L R R L T 3 Q V A I C L A L I S G Q L L I V V A W L 4 A Y L T C L A I L L V N Y A L S G L M S 5 G F T M Y T T C I I W L A F L P I F Y V 6 G L V V S G S L S V S V C M T T T Q V R 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term G D A W A V G P V T I A C L G A L A T L F V L G V F V R H G R E L C Y I L L G G V F L C Y C M T F I F I A S T A V C T L R R L G L G T A F S V C Y S A L L T K T N R I A R I F G G S P A S Q V A I C L A L I S G Q L L I V V A W L V V E D A S M L G S L A Y N V L L I A L C T L Y A F K T R K C F N E A K F I G F T M Y T T C I I W L A F L P I F Y V T S D Y R V Q T T T M C V S V S L S G S V V L G C L F A P K L H I I L F Q P Q K H R A N V V S P T
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Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu2 receptor