Structure information

HCA3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8JEF

SPECIES

Homo sapiens

RESOLUTION

2.960

PREFERRED CHAIN

A

REFERENCE

10.1016/J.CELREP.2024.114895

PUBLICATION DATE

Dec. 18, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
3-hydroxyoctanoic acid R22 N-term polar (charge-assisted hydrogen bond)
3-hydroxyoctanoic acid V83 2.60x60 TM2 Van der Waals
3-hydroxyoctanoic acid V83 2.60x60 TM2 hydrophobic
3-hydroxyoctanoic acid F107 3.32x32 TM3 Van der Waals
3-hydroxyoctanoic acid F107 3.32x32 TM3 hydrophobic
3-hydroxyoctanoic acid F180 ECL2 Van der Waals
3-hydroxyoctanoic acid Y284 7.43x42 TM7 polar (hydrogen bond)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 7 of 7 entries

Ligands

3-hydroxyoctanoic acid

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Residue Diagrams

G N G L L G F I F E L G L V P P L V K A 1 F N L A V A D F L L I I C L P F V M D Y 2 V T L F I I S G Q R N M A F M F L V L R 3 A A I I S C L L W G I T V G L T V H L L 4 S C F L I I G L P L F F E L L F M A E H W 5 M V V A I V F V I C F L P S V V V R I H 6 V P D L M S N M Y T F S L T I F F A L 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term D D F I A K V L P P V L G L E F I F G L L G N G L A L W I F C F H K S S R I F L F N L A V A D F L L I I C L P F V M D Y Y V R G D I P C R L V L F M F A M N R Q G S I I F L T V V A V D R Y F R V V H S N W T A A I I S C L L W G I T V G L T V H L L K K K R W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R K I K R A I T F I M V V A I V F V I C F L P S V V V R I H I F W L L H T S V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F S T F P N F L I N
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Residue Table


GPCRdb(A)
GPCRdb(A)
HCA3 receptor
TM2
2x60 2.60x60 V83
TM3
3x32 3.32x32 F107
TM7
7x42 7.43x42 Y284