Structure information

HCA2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8JHY

SPECIES

Homo sapiens

RESOLUTION

2.870

PREFERRED CHAIN

A

REFERENCE

10.1016/J.MOLCEL.2023.07.030

PUBLICATION DATE

Sept. 6, 2023
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
compound 9n [PMID: 18752940] H184 ECL2 aromatic (edge-to-face)
compound 9n [PMID: 18752940] F186 ECL2 hydrophobic
compound 9n [PMID: 18752940] A191 5.41x42 TM5 Van der Waals
compound 9n [PMID: 18752940] A191 5.41x42 TM5 polar (hydrogen bond with backbone)
compound 9n [PMID: 18752940] L194 5.44x45 TM5 Van der Waals
compound 9n [PMID: 18752940] L194 5.44x45 TM5 hydrophobic
compound 9n [PMID: 18752940] L195 5.45x46 TM5 hydrophobic
compound 9n [PMID: 18752940] L195 5.45x46 TM5 Van der Waals
compound 9n [PMID: 18752940] F198 5.48x48 TM5 hydrophobic
compound 9n [PMID: 18752940] F255 6.59x59 TM6 hydrophobic
compound 9n [PMID: 18752940] F255 6.59x59 TM6 Van der Waals
compound 9n [PMID: 18752940] L258 6.62x62 TM6 Van der Waals
compound 9n [PMID: 18752940] L258 6.62x62 TM6 hydrophobic
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 13 of 13 entries

Ligands

compound 9n [PMID: 18752940]

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Residue Diagrams

G N G L L G F I F E L G L V P P L V K V 1 F N L A V A D F L L I I C L P F L M D N 2 V T L F I I S G Q R N M A L M F L M L R 3 A A I I S C L L W G I T I G L T V H L L 4 S C F L I I G L P L F F E L L F M A E H W 5 M V V A I V F V I C F L P S V V V R I R 6 V P D L M S N M Y T F S L T I F F A L 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term F I V K V L P P V L G L E F I F G L L G N G L A L W I F C F H K S S R I F L F N L A V A D F L L I I C L P F L M D N Y V R R G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H S N R T A A I I S C L L W G I T I G L T V H L L K K K Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F S T C L F P N F L I N R
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Residue Table


GPCRdb(A)
GPCRdb(A)
HCA2 receptor
TM5
5x42 5.41x42 A191
5x45 5.44x45 L194
5x46 5.45x46 L195
5x48 5.48x48 F198
TM6
6x59 6.59x59 F255
6x62 6.62x62 L258