Structure information

CXCR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8K2X

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

R

REFERENCE

10.1038/S41421-023-00617-0

PUBLICATION DATE

Nov. 29, 2023

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
C-X-C motif chemokine 10 D52 1.31x31 TM1 polar (charge-assisted hydrogen bond)
C-X-C motif chemokine 10 Y60 1.39x39 TM1 Van der Waals
C-X-C motif chemokine 10 W109 2.60x60 TM2 Van der Waals
C-X-C motif chemokine 10 W109 2.60x60 TM2 hydrophobic
C-X-C motif chemokine 10 F131 3.32x32 TM3 hydrophobic
C-X-C motif chemokine 10 F131 3.32x32 TM3 Van der Waals
C-X-C motif chemokine 10 Q204 45.51x51 ECL2 polar (hydrogen bond)
C-X-C motif chemokine 10 Y205 45.52x52 ECL2 hydrophobic
C-X-C motif chemokine 10 Y205 45.52x52 ECL2 Van der Waals
C-X-C motif chemokine 10 R212 5.35x36 TM5 polar (charge-assisted hydrogen bond)
C-X-C motif chemokine 10 Y271 6.51x51 TM6 hydrophobic
C-X-C motif chemokine 10 Y271 6.51x51 TM6 Van der Waals
C-X-C motif chemokine 10 C290 7.25x24 TM7 polar (hydrogen bond)
C-X-C motif chemokine 10 C290 7.25x24 TM7 polar (hydrogen bond with backbone)
C-X-C motif chemokine 10 E293 7.28x27 TM7 Van der Waals
C-X-C motif chemokine 10 K300 7.35x34 TM7 Van der Waals
C-X-C motif chemokine 10 S304 7.39x38 TM7 polar (hydrogen bond)
C-X-C motif chemokine 10 S304 7.39x38 TM7 Van der Waals
C-X-C motif chemokine 10 Y308 7.43x42 TM7 polar (hydrogen bond)
C-X-C motif chemokine 10 Y308 7.43x42 TM7 polar (hydrogen bond)

Ligands

C-X-C motif chemokine 10

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N G L L G L L F L L S Y L A P L F A R 1 L H L A V A D T L L V L T L P L W A V D 2 C A L L L A G A Y F N I N F L A G A V K 3 V T L T C L A V W G L C L L F A L P D 4 Y C Y A M V L L P L L F G A V L Q L V R L 5 V V V V V A F A L C W T P Y H L V V L V 6 L P N L C C H M Y G L G S T V S K A V 7
Download: PNG | SVG
ICL1 R T A L ICL1ECL1 Q W V F ECL1ICL2 A T Q L Y R R G P P ICL2ECL2 S A H H D E R L N A T H C Q Y N F ECL2ICL3 R G Q ICL3ECL3 A L A R ECL3N-term M V L E V S D H Q V L N D A E V A A L L E N F S S S Y D Y G E N E S D S C C T S P P C P N-termC-term G C P N Q R G L Q R Q P S S S R R D S S W S E T S E A S Y S G L C-term Q D F S L N F D R A F L P A L Y S L L F L L G L L G N G A V A A V L L S R S S T D T F L L H L A V A D T L L V L T L P L W A V D A A V G S G L C K V A G A L F N I N F Y A G A L L L A C I S F D R Y L N I V H A R V T L T C L A V W G L C L L F A L P D F I F L P Q V G R T A L R V L Q L V A G F L L P L L V M A Y C Y A H I L A V L L V S R R L R A M R L V V V V V V A F A L C W T P Y H L V V L V D I L M D L G N C G R E S R V D V A K S V T S G L G Y M H C C L N P L L Y A F V G V K M W M L F R E R L L L R
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
CXCR3
TM1
1x31 1.31x31 D52
1x39 1.39x39 Y60
TM2
2x60 2.60x60 W109
TM3
3x32 3.32x32 F131
ECL2
45x51 45.51x51 Q204
45x52 45.52x52 Y205
TM5
5x36 5.35x36 R212
TM6
6x51 6.51x51 Y271
TM7
7x24 7.25x24 C290
7x27 7.28x27 E293
7x34 7.35x34 K300
7x38 7.39x38 S304
7x42 7.43x42 Y308