Structure information

MRGPRX4

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8K4S

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

E

REFERENCE

10.1016/J.CELL.2024.10.001

PUBLICATION DATE

Nov. 6, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
DCA-3P V99 3.29x29 TM3 hydrophobic
DCA-3P F107 3.37x37 TM3 hydrophobic
DCA-3P L156 ECL2 hydrophobic
DCA-3P I239 ECL3 hydrophobic
DCA-3P Y240 ECL3 hydrophobic
DCA-3P L246 ECL3 hydrophobic
DCA-3P Y254 7.35x34 TM7 hydrophobic
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 7 of 7 entries

Ligands

DCA-3P

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Residue Diagrams

A N G T L G V L S I I C T L V T F S L T 1 L N L A A A D F L F L S F Q I I R L P L 2 A S L M S L G T F Y P F T M V S V L I K 3 S A V V C V L L W G L S L L F S M L E W 4 S S V C L V V C L F I L W A V P I F D S 5 L L T V L V F L L C G L P F G I L G A L 6 I P N A S S N L S S L S M C V L Y V H 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term Q T L S F T V L T C I I S L V G L T G N A V V L W L L G Y R M N A V S I Y I L N L A A A D F L F L S F Q I I R L P L R L S H L I R K I L V S V M T F P Y F T G L S M L S A I S T E R C L S V L W H L S A V V C V L L W G L S L L F S M L E W R F C D S S W C E T S D F I P V A W L I F L C V V L C V S S L V L L V R I L C P L T R L Y V T I L L T V L V F L L C G L P F G I L G A L V L Y C H V Y L V C M S L S S L N S S A N P I I Y F F V G S F R
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Residue Table


GPCRdb(A)
GPCRdb(A)
MRGPRX4
TM3
3x29 3.29x29 V99
3x37 3.37x37 F107
TM7
7x34 7.35x34 Y254