Structure information

μ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8K9K

SPECIES

Homo sapiens

RESOLUTION

2.980

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-024-47792-6

PUBLICATION DATE

May 29, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
DAMGO I146 3.29x29 TM3 hydrophobic
DAMGO Y150 3.33x33 TM3 hydrophobic
DAMGO M153 3.36x36 TM3 hydrophobic
DAMGO V238 5.42x43 TM5 hydrophobic
DAMGO I298 6.51x51 TM6 hydrophobic
DAMGO V302 6.55x55 TM6 hydrophobic
DAMGO W320 7.35x34 TM7 hydrophobic
DAMGO I324 7.39x38 TM7 hydrophobic

Ligands

DAMGO

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Residue Diagrams

F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I I N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 T T K Y R Q G S I D C T L T F S H ECL2ICL3 R M L S G ICL3ECL3 T I P E ECL3N-term M D S S A A P T N A S N C T D A L A Y S S C S P A P S P G S W V N L S H L D G N L S D P C G P N R T D L G G R D S L C P P T G S P S N-termC-term P T S S N I E Q Q N S T R I R Q N T R D H P S T A N T V D R T N H Q L E N L E A E T A P L P C-term M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I I N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
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Residue Table


GPCRdb(A)
GPCRdb(A)
μ receptor
TM3
3x29 3.29x29 I146
3x33 3.33x33 Y150
3x36 3.36x36 M153
TM5
5x43 5.42x43 V238
TM6
6x51 6.51x51 I298
6x55 6.55x55 V302
TM7
7x34 7.35x34 W320
7x38 7.39x38 I324