Structure information

H2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8POK

SPECIES

Homo sapiens

RESOLUTION

3.400

PREFERRED CHAIN

A

REFERENCE

10.1038/S41467-024-46096-Z

PUBLICATION DATE

March 6, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
histamine D104 3.32x32 TM3 polar (hydrogen bond with backbone)
histamine D104 3.32x32 TM3 polar (charge-assisted hydrogen bond)
histamine V105 3.33x33 TM3 Van der Waals
LigandAmino AcidGeneric NumberSegmentInteraction Type
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Ligands

histamine

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Residue Diagrams

V N G A V T I L I L V A L V V T I T I K 1 V S L A I T D L L L G L L V L P F S A I Y 2 M F L N L I S A T C L M V D L S T Y I N 3 V A I S L V L I W V I S I T L S F L S I 4 Y T I C M I L L P L Y F T V L G D V L G Y 5 A A V M G A F I I C W F P Y F T A F V Y 6 I P N L A S N A Y G L W L V I A E L V 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term F C L D S T A C K I T I T V V L A V L I L I T V A G N V V V C L A V G L N N L T N C F I V S L A I T D L L L G L L V L P F S A I Y Q L S C G K V F C N I Y T S L D V M L C T A S I L N L F M I S L D R Y C A V M D T P V R V A I S L V L I W V I S I T L S F L S I H L G N E V Y G L V D G L V T F Y L P L L I M C I T Y Y R I F K V A R D Q A K R I N S W K A A T I R E H K A T V T L A A V M G A F I I C W F P Y F T A F V Y R G L R N E V L E A I V L W L G Y A N S A L N P I L Y A A L N R D Y Q Q F R T G L F C
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Residue Table


GPCRdb(A)
GPCRdb(A)
H2 receptor
TM3
3x32 3.32x32 D98
3x33 3.33x33 V99