Structure information

TA1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8WCA

SPECIES

Homo sapiens

RESOLUTION

3.480

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELL.2023.10.014

PUBLICATION DATE

Dec. 27, 2023
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
2-Phenylethanaminium D103 3.32x32 TM3 polar (charge-charge)
2-Phenylethanaminium I104 3.33x33 TM3 hydrophobic
2-Phenylethanaminium I104 3.33x33 TM3 Van der Waals
2-Phenylethanaminium S107 3.36x36 TM3 Van der Waals
2-Phenylethanaminium F267 6.51x51 TM6 aromatic (edge-to-face)
2-Phenylethanaminium F267 6.51x51 TM6 Van der Waals
2-Phenylethanaminium F268 6.52x52 TM6 Van der Waals
2-Phenylethanaminium F268 6.52x52 TM6 aromatic (edge-to-face)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 8 of 8 entries

Ligands

2-Phenylethanaminium

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Residue Diagrams

L N G V L T T L I I L V M L S Y L S A R 1 H S M A T V D F L L G L C V M P Y S M V R 2 F S L H F I S A S S L M I D T S T H I K 3 I C V M I F I S W S V P A V F A F G M I 4 Y V C L M I S G P I Y F S T M F T L V G S 5 G I V M G V F L I C W C P F F I C T V M 6 M P N F T S N L Y G F W I L V D N L T 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term D V R A S L Y S L M V L I I L T T L V G N L I V I V S I S H F T P T N W L I H S M A T V D F L L G C L V M P Y S M V R S A E H G E V F C K I H T S T D I M L S S A S I F H L S F I S I D R Y Y A V C D N I L V I C V M I F I S W S V P A V F A F G M I F L E S K I S G V L T F M T S F Y I P G S I M L C V Y Y R I Y L I A K E Q A R L I S D A N Q K L Q N G I S Q S K E R K A V K T L G I V M G V F L I C W C P F F I C T V M D P F L P P T L N D V L I W F G Y L N S T F N P M V Y A F F Y P W L K M F R K A M L F
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Residue Table


GPCRdb(A)
GPCRdb(A)
TA1 receptor
TM3
3x32 3.32x32 D103
3x33 3.33x33 I104
3x36 3.36x36 S107
TM6
6x51 6.51x51 F267
6x52 6.52x52 F268