PDB
8Y71
Resolution
3.0 Å
Released
Jan. 7, 2026
Receptor
δ
Class
A
Species
Homo sapiens
Ligands
Function
SNC80
Agonist
BMS-986187
PAM
Reference
—
SNC80 BMS-986187

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
BMS-986187 L97 2.52x52 TM2 hydrophobic
BMS-986187 L120 3.24x24 TM3 Van der Waals
BMS-986187 A123 3.27x27 TM3 hydrophobic
BMS-986187 S126 3.30x30 TM3 polar (hydrogen bond)
BMS-986187 I127 3.31x31 TM3 hydrophobic
SNC80 D128 3.32x32 TM3 polar (charge-charge)
SNC80 Y129 3.33x33 TM3 aromatic (pi-cation)
BMS-986187 Y130 3.34x34 TM3 hydrophobic
BMS-986187 N131 3.35x35 TM3 Van der Waals
SNC80 M132 3.36x36 TM3 Van der Waals
BMS-986187 W173 4.50x50 TM4 hydrophobic
BMS-986187 S177 4.54x54 TM4 Van der Waals
BMS-986187 G180 4.57x57 TM4 Van der Waals
BMS-986187 M184 4.61x61 TM4 hydrophobic
SNC80 K214 5.39x40 TM5 Van der Waals
SNC80 V217 5.42x43 TM5 hydrophobic
SNC80 F218 5.43x44 TM5 Van der Waals
SNC80 W274 6.48x48 TM6 hydrophobic
SNC80 I277 6.51x51 TM6 hydrophobic
SNC80 H278 6.52x52 TM6 aromatic (edge-to-face)
SNC80 V281 6.55x55 TM6 hydrophobic
SNC80 I282 6.56x56 TM6 Van der Waals
SNC80 W284 6.58x58 TM6 hydrophobic
SNC80 L300 7.35x34 TM7 hydrophobic
SNC80 I304 7.39x38 TM7 Van der Waals
SNC80 G307 7.42x41 TM7 Van der Waals
SNC80 Y308 7.43x42 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 V T R P R D G A V V C M L Q F P S ECL2ICL3 R L L S G ICL3ECL3 D I D R R ECL3N-term M E P A P S A G A E L Q P P L F A N A S D A Y P S A C P S A G A N A S G P P N-termC-term P C G R P D P S S F S R A R E A T A R E R V T A C T P S D G P G G G A A A C-term G A R S A S S L A L A I A I T A L Y S A V C A V G L L G N V L V M F G I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S A K Y L M E G E L L C K A V L S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P A K A K L I N I C I W V L A S G V G V P I M V M A P S W Y W D T V T K I C V F L F A F V V P I L I I T V C Y G L M L L R L R S V S K E K D R S L R R I T R M V L V V V G A F V V C W A P I H I F V I V W T L V D P L V V A A L H L C I A L G Y A N S S L N P V L Y A F L D E N F R Q F K R C L C R K
Helix box plot — Download: PNG | SVG V N G L L G V A C V A S Y L A T I A I A 1 F N L A L A D A L A T S T L P F Q S A K 2 M T L T F I S T F M N Y Y D I S L V A K 3 A K L I N I C I W V L A S G V G V P I M 4 Y C V T I I L I P V V F A F L F V C I K T 5 L V V V G A F V V C W A P I H I F V I V 6 V P N L S S N A Y G L A I C L H L A A 7

GPCRdb(A)
GPCRdb(A)
δ receptor
TM2
2x52 2.52x52 L97
TM3
3x24 3.24x24 L120
3x27 3.27x27 A123
3x30 3.30x30 S126
3x31 3.31x31 I127
3x32 3.32x32 D128
3x33 3.33x33 Y129
3x34 3.34x34 Y130
3x35 3.35x35 N131
3x36 3.36x36 M132
TM4
4x50 4.50x50 W173
4x54 4.54x54 S177
4x57 4.57x57 G180
4x61 4.61x61 M184
TM5
5x40 5.39x40 K214
5x43 5.42x43 V217
5x44 5.43x44 F218
TM6
6x48 6.48x48 W274
6x51 6.51x51 I277
6x52 6.52x52 H278
6x55 6.55x55 V281
6x56 6.56x56 I282
6x58 6.58x58 W284
TM7
7x34 7.35x34 L300
7x38 7.39x38 I304
7x41 7.42x41 G307
7x42 7.43x42 Y308